Magnesium in PDB 5tey: Human METTL3-METTL14 Complex

All present enzymatic activity of Human METTL3-METTL14 Complex:
2.1.1.62;

The structure of Human METTL3-METTL14 Complex, PDB code: 5tey was solved by A.Dong, H.Zeng, Y.Li, W.Tempel, A.Seitova, A.Hutchinson, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	63.883, 63.883, 225.709, 90.00, 90.00, 120.00
R / Rfree (%)	19.8 / 22.4

The binding sites of Magnesium atom in the Human METTL3-METTL14 Complex (pdb code 5tey). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human METTL3-METTL14 Complex, PDB code: 5tey:

Magnesium binding site 1 out of 1 in the Human METTL3-METTL14 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human METTL3-METTL14 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:43.3 occ:1.00 O A:HOH726 2.0 35.6 1.0 O A:HOH741 2.1 46.5 1.0 O A:HOH705 2.2 27.3 1.0 O A:HOH776 2.2 44.5 1.0 OE1 A:GLU506 2.3 39.7 1.0 O B:ASN117 3.1 53.4 1.0 CD A:GLU506 3.2 37.4 1.0 OE2 A:GLU506 3.5 39.2 1.0 OE2 A:GLU516 4.0 24.5 1.0 C B:ASN117 4.3 48.1 1.0 O A:HOH789 4.4 38.6 1.0 O A:HOH722 4.4 27.7 1.0 O A:HOH723 4.5 35.2 1.0 N B:ASN117 4.5 48.9 1.0 N A:GLU506 4.5 26.1 1.0 O A:HOH710 4.6 31.4 1.0 CG A:GLU506 4.6 33.7 1.0 CA A:ALA505 4.9 23.5 1.0 CA B:ASN117 4.9 47.9 1.0 CB A:GLU506 4.9 31.0 1.0

H.Zeng, A.Dong, Y.Li, W.Tempel, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, H.Wu, Structural Genomics Consortium (Sgc). Human METTL3-METTL14 Complex To Be Published.