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Magnesium in PDB 5tfb: Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-GtpEnzymatic activity of Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp
All present enzymatic activity of Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp:
3.6.3.49; Protein crystallography data
The structure of Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp, PDB code: 5tfb
was solved by
C.Wang,
A.A.Aleksandrov,
Z.Yang,
F.Forouhar,
E.Proctor,
P.Kota,
J.An,
A.Kaplan,
N.Khazanov,
G.Boel,
B.R.Stockwell,
H.Senderowitz,
N.V.Dokholyan,
J.R.Riordan,
C.G.Brouillette,
J.F.Hunt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp
(pdb code 5tfb). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp, PDB code: 5tfb: Magnesium binding site 1 out of 1 in 5tfbGo back to Magnesium Binding Sites List in 5tfb
Magnesium binding site 1 out
of 1 in the Nucleotide-Binding Domain 1 of the Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) with 7-Methyl-Gtp
Mono view Stereo pair view
Reference:
C.Wang,
A.A.Aleksandrov,
Z.Yang,
F.Forouhar,
E.Proctor,
P.Kota,
J.An,
A.Kaplan,
N.Khazanov,
G.Boel,
B.R.Stockwell,
H.Senderowitz,
N.V.Dokholyan,
J.R.Riordan,
C.G.Brouillette,
J.F.Hunt.
Thermodynamic Correction of F508DEL-Cftr By Ligand Binding to A Remote Site in the Mutated Domain To Be Published.
Page generated: Mon Dec 14 21:11:55 2020
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