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Magnesium in PDB 5tuq: Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse TranscriptaseEnzymatic activity of Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase
All present enzymatic activity of Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase:
2.7.7.49; 2.7.7.7; 3.1.13.2; 3.1.26.13; 3.4.23.16; Protein crystallography data
The structure of Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase, PDB code: 5tuq
was solved by
K.A.Kirby,
S.G.Sarafianos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase
(pdb code 5tuq). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase, PDB code: 5tuq: Magnesium binding site 1 out of 1 in 5tuqGo back to Magnesium Binding Sites List in 5tuq
Magnesium binding site 1 out
of 1 in the Crystal Structure of A 6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4- Dione Inhibitor in Complex with Hiv Reverse Transcriptase
Mono view Stereo pair view
Reference:
J.Tang,
K.A.Kirby,
A.D.Huber,
M.C.Casey,
J.Ji,
D.J.Wilson,
S.G.Sarafianos,
Z.Wang.
6-Cyclohexylmethyl-3-Hydroxypyrimidine-2,4-Dione As An Inhibitor Scaffold of Hiv Reverase Transcriptase: Impacts of the 3-Oh on Inhibiting Rnase H and Polymerase. Eur J Med Chem V. 128 168 2017.
Page generated: Mon Dec 14 21:13:00 2020
ISSN: ISSN 1768-3254 PubMed: 28182989 DOI: 10.1016/J.EJMECH.2017.01.041 |
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