Magnesium in PDB 5u99: Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase

All present enzymatic activity of Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase:
2.4.2.17;

The structure of Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase, PDB code: 5u99 was solved by G.-J.Moggre, M.B.Poulin, P.C.Tyler, V.L.Schramm, E.J.Parker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	80.43 / 2.40
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	134.758, 134.758, 111.005, 90.00, 90.00, 120.00
R / Rfree (%)	21.6 / 25.1

The binding sites of Magnesium atom in the Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase (pdb code 5u99). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase, PDB code: 5u99:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg304 b:48.1 occ:1.00 O A:HOH411 1.9 41.6 1.0 O1B A:ATP306 2.0 39.8 1.0 O A:HOH412 2.2 31.0 1.0 O1A A:ATP306 2.3 36.3 1.0 O3G A:ATP306 2.4 40.0 1.0 O A:HOH418 2.4 38.8 1.0 PB A:ATP306 3.2 41.1 1.0 PA A:ATP306 3.5 40.0 1.0 PG A:ATP306 3.5 40.2 1.0 O3B A:ATP306 3.7 38.9 1.0 O3A A:ATP306 3.7 39.9 1.0 O A:HOH404 4.1 34.6 1.0 O1G A:ATP306 4.1 38.9 1.0 O3 A:SO4302 4.2 41.9 1.0 C5' A:ATP306 4.3 42.3 1.0 O5' A:ATP306 4.4 39.6 1.0 O4 A:SO4302 4.5 45.9 1.0 O2B A:ATP306 4.5 40.4 1.0 O2A A:ATP306 4.7 38.5 1.0 N3 A:ATP306 4.7 40.5 1.0 C2 A:ATP306 4.8 41.9 1.0 S A:SO4302 4.8 43.0 1.0 O2G A:ATP306 4.8 38.7 1.0 O1 A:SO4302 5.0 44.4 1.0

Magnesium binding site 2 out of 2 in the Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg305 b:66.7 occ:0.50 O A:HOH403 1.7 54.4 1.0 O1G A:ATP306 2.3 38.9 1.0 O A:HOH425 2.7 52.4 1.0 PG A:ATP306 3.4 40.2 1.0 O3B A:ATP306 3.7 38.9 1.0 O2G A:ATP306 3.9 38.7 1.0 O A:HOH404 3.9 34.6 1.0 NH1 A:ARG49 4.0 44.5 1.0 OD2 A:ASP137 4.3 42.0 1.0 O2B A:ATP306 4.3 40.4 1.0 PB A:ATP306 4.5 41.1 1.0 OD1 A:ASP137 4.5 43.7 1.0 O3G A:ATP306 4.8 40.0 1.0 CG A:ASP137 4.8 43.1 1.0 O1B A:ATP306 4.9 39.8 1.0

G.J.Moggre, M.B.Poulin, P.C.Tyler, V.L.Schramm, E.J.Parker. Transition State Analysis of Adenosine Triphosphate Phosphoribosyltransferase. Acs Chem. Biol. V. 12 2662 2017.
ISSN: ESSN 1554-8937
PubMed: 28872824
DOI: 10.1021/ACSCHEMBIO.7B00484