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Atomistry » Magnesium » PDB 5uhc-5use » 5ukl » |
Magnesium in PDB 5ukl: Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD)Enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD)
All present enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD):
2.7.11.15; Protein crystallography data
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD), PDB code: 5ukl
was solved by
M.C.Cato,
K.T.Homan,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5ukl:
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD) also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD)
(pdb code 5ukl). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD), PDB code: 5ukl: Magnesium binding site 1 out of 1 in 5uklGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Human GRK2 in Complex with Gbetagamma Subunits and CCG222886 (14BD)
![]() Mono view ![]() Stereo pair view
Reference:
H.V.Waldschmidt,
K.T.Homan,
M.C.Cato,
O.Cruz-Rodriguez,
A.Cannavo,
M.W.Wilson,
J.Song,
J.Y.Cheung,
W.J.Koch,
J.J.Tesmer,
S.D.Larsen.
Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem. V. 60 3052 2017.
Page generated: Mon Sep 30 05:22:22 2024
ISSN: ISSN 1520-4804 PubMed: 28323425 DOI: 10.1021/ACS.JMEDCHEM.7B00112 |
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