Atomistry » Magnesium » PDB 5v60-5voi » 5vj3
Atomistry »
  Magnesium »
    PDB 5v60-5voi »
      5vj3 »

Magnesium in PDB 5vj3: Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site

Enzymatic activity of Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site

All present enzymatic activity of Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site:
3.4.23.16;

Protein crystallography data

The structure of Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site, PDB code: 5vj3 was solved by T.Tiefenbrunn, C.D.Stout, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.47 / 2.00
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 48.925, 48.925, 103.012, 90.00, 90.00, 90.00
R / Rfree (%) 21.9 / 27.9

Other elements in 5vj3:

The structure of Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site also contains other interesting chemical elements:

Fluorine (F) 3 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site (pdb code 5vj3). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site, PDB code: 5vj3:

Magnesium binding site 1 out of 1 in 5vj3

Go back to Magnesium Binding Sites List in 5vj3
Magnesium binding site 1 out of 1 in the Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Hiv Protease (Pr) in Open Form with MG2+ in Active Site and Hive-9 in Eye Site within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1102

b:46.8
occ:0.50
 O A:HOH1233 2.0 49.6 0.5
O A:HOH1224 2.1 43.8 0.5
O A:HOH1207 2.1 45.5 0.5
O A:HOH1227 2.2 50.1 0.5
O A:HOH1212 2.2 40.4 0.5
O A:HOH1209 2.3 36.9 0.5
O A:HOH1218 3.7 50.1 1.0
OD2 A:ASP1025 4.0 35.6 1.0
OD1 A:ASP1025 4.3 35.0 1.0
C29 A:HV91101 4.5 61.9 0.8
N08 A:HV91101 4.5 60.3 0.8
CG A:ASP1025 4.6 38.6 1.0
O A:GLY1027 4.7 38.6 1.0
C A:GLY1027 4.7 38.1 1.0
CA A:GLY1027 4.9 33.9 1.0
N10 A:HV91101 4.9 57.4 0.8

Reference:

S.Forli, T.Tiefenbrunn, M.M.Baksh, M.W.Chang, A.Perryman, D.Garg, M.Happer, Y.-C.Lin, D.Goodsell, E.L.Angelina, I.De Vera, D.Kojetin, B.E.Torbett, M.G.Finn, J.Elder, C.D.Stout, A.Olson. Fragment-Based Campaign For the Identification of Potential Exosite Binders of Hiv-1 Protease To Be Published.
Page generated: Mon Sep 30 06:10:25 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy