Magnesium in PDB 5w81: Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)

All present enzymatic activity of Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):
3.6.3.49;

The binding sites of Magnesium atom in the Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) (pdb code 5w81). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr), PDB code: 5w81:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1503 b:0.3 occ:1.00 O2B A:ATP1501 2.0 0.5 1.0 OG A:SER464 2.1 0.1 1.0 OE1 A:GLN492 2.2 0.3 1.0 O3G A:ATP1501 2.2 0.5 1.0 PB A:ATP1501 3.1 0.7 1.0 CD A:GLN492 3.3 0.3 1.0 CB A:SER464 3.4 0.6 1.0 O3B A:ATP1501 3.4 0.1 1.0 PG A:ATP1501 3.4 0.5 1.0 O1B A:ATP1501 3.7 0.5 1.0 NE2 A:GLN492 3.7 0.5 1.0 OD2 A:ASP571 3.8 0.6 1.0 OD1 A:ASP571 4.0 0.2 1.0 N A:SER464 4.1 0.4 1.0 CA A:SER464 4.2 0.0 1.0 O2G A:ATP1501 4.3 1.0 1.0 CG A:ASP571 4.3 0.4 1.0 O3A A:ATP1501 4.4 0.0 1.0 O1G A:ATP1501 4.5 0.3 1.0 O1A A:ATP1501 4.6 0.9 1.0 CG A:GLN492 4.6 0.2 1.0 PA A:ATP1501 4.9 0.9 1.0 O2A A:ATP1501 4.9 0.1 1.0 NZ A:LYS463 4.9 0.4 1.0 CB A:GLN492 4.9 0.6 1.0

Magnesium binding site 2 out of 2 in the Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Phosphorylated, Atp-Bound Structure of Zebrafish Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1504 b:0.6 occ:1.00 O2B A:ATP1502 1.9 0.8 1.0 OE1 A:GLN1292 2.0 0.6 1.0 O2G A:ATP1502 2.2 0.1 1.0 OG A:SER1252 2.3 0.2 1.0 PB A:ATP1502 3.2 0.9 1.0 CD A:GLN1292 3.2 0.2 1.0 PG A:ATP1502 3.5 0.1 1.0 O3B A:ATP1502 3.5 0.6 1.0 CB A:SER1252 3.5 0.0 1.0 OD1 A:ASP1371 3.9 0.0 1.0 NE2 A:GLN1292 3.9 0.0 1.0 O1B A:ATP1502 4.0 0.4 1.0 OD2 A:ASP1371 4.0 0.5 1.0 O2A A:ATP1502 4.3 0.5 1.0 N A:SER1252 4.3 0.2 1.0 O1G A:ATP1502 4.3 0.9 1.0 CG A:ASP1371 4.4 0.6 1.0 CG A:GLN1292 4.4 0.5 1.0 O3A A:ATP1502 4.4 0.0 1.0 CA A:SER1252 4.5 0.5 1.0 O3G A:ATP1502 4.6 1.0 1.0 NE2 A:GLN1372 4.6 0.5 1.0 N A:GLY549 4.6 0.3 1.0 PA A:ATP1502 4.7 0.1 1.0 CB A:GLN1292 4.7 0.9 1.0 O1A A:ATP1502 4.8 0.3 1.0

Z.Zhang, F.Liu, J.Chen. Conformational Changes of Cftr Upon Phosphorylation and Atp Binding. Cell V. 170 483 2017.
ISSN: ISSN 1097-4172
PubMed: 28735752
DOI: 10.1016/J.CELL.2017.06.041