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Magnesium in PDB 5wg3: Human GRK2 in Complex with Gbetagamma Subunits and CCG258748Enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG258748
All present enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG258748:
2.7.11.15; Protein crystallography data
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG258748, PDB code: 5wg3
was solved by
R.Bouley,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5wg3:
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG258748 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human GRK2 in Complex with Gbetagamma Subunits and CCG258748
(pdb code 5wg3). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human GRK2 in Complex with Gbetagamma Subunits and CCG258748, PDB code: 5wg3: Magnesium binding site 1 out of 1 in 5wg3Go back to Magnesium Binding Sites List in 5wg3
Magnesium binding site 1 out
of 1 in the Human GRK2 in Complex with Gbetagamma Subunits and CCG258748
Mono view Stereo pair view
Reference:
R.Bouley,
H.V.Waldschmidt,
M.C.Cato,
A.Cannavo,
J.Song,
J.Y.Cheung,
X.Q.Yao,
W.J.Koch,
S.D.Larsen,
J.J.G.Tesmer.
Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors. Mol. Pharmacol. V. 92 707 2017.
Page generated: Mon Dec 14 21:21:07 2020
ISSN: ESSN 1521-0111 PubMed: 29070696 DOI: 10.1124/MOL.117.110130 |
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