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Magnesium in PDB 5wg5: Human GRK2 in Complex with Gbetagamma Subunits and CCG224061Enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG224061
All present enzymatic activity of Human GRK2 in Complex with Gbetagamma Subunits and CCG224061:
2.7.11.15; Protein crystallography data
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG224061, PDB code: 5wg5
was solved by
R.Bouley,
J.J.G.Tesmer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5wg5:
The structure of Human GRK2 in Complex with Gbetagamma Subunits and CCG224061 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human GRK2 in Complex with Gbetagamma Subunits and CCG224061
(pdb code 5wg5). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human GRK2 in Complex with Gbetagamma Subunits and CCG224061, PDB code: 5wg5: Magnesium binding site 1 out of 1 in 5wg5Go back to Magnesium Binding Sites List in 5wg5
Magnesium binding site 1 out
of 1 in the Human GRK2 in Complex with Gbetagamma Subunits and CCG224061
Mono view Stereo pair view
Reference:
R.Bouley,
H.V.Waldschmidt,
M.C.Cato,
A.Cannavo,
J.Song,
J.Y.Cheung,
X.Q.Yao,
W.J.Koch,
S.D.Larsen,
J.J.G.Tesmer.
Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein-Coupled Receptor Kinase 2 Inhibitors. Mol. Pharmacol. V. 92 707 2017.
Page generated: Mon Dec 14 21:21:07 2020
ISSN: ESSN 1521-0111 PubMed: 29070696 DOI: 10.1124/MOL.117.110130 |
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