Magnesium in PDB 5y19: Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide.

The structure of Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide., PDB code: 5y19 was solved by A.K.Marapaka, Y.Zhang, A.Addlagatta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.96 / 1.83
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	74.988, 109.258, 112.238, 90.00, 90.00, 90.00
R / Rfree (%)	16.6 / 20.7

The structure of Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide. also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Magnesium atom in the Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide. (pdb code 5y19). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide., PDB code: 5y19:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1102 b:38.5 occ:1.00 O A:HOH1595 2.1 7.5 0.2 O A:HOH1584 2.1 38.4 1.0 O A:HOH1495 2.1 33.3 1.0 O A:HOH1596 2.2 28.1 0.5 O A:HOH1410 2.2 34.5 1.0 O A:HOH1316 2.2 33.2 1.0 OE2 A:GLU957 3.8 30.4 1.0 O A:HOH1241 4.1 33.1 1.0 O A:HOH1597 4.2 31.5 1.0 ND2 A:ASN992 4.2 31.9 1.0 OD2 A:ASP995 4.3 30.4 1.0 O A:HOH1454 4.6 31.2 1.0 O A:HOH1350 4.6 35.3 1.0 CD A:GLU957 4.6 34.7 1.0 CG A:GLU957 4.8 36.4 1.0 CE A:LYS311 4.9 35.4 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy- 4-Methylpentanamide. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1103 b:35.6 occ:1.00 O A:GLY250 2.1 24.5 1.0 O A:HOH1459 2.1 32.3 1.0 O A:HOH1532 2.1 29.4 1.0 O A:HOH1286 2.2 26.6 1.0 C A:GLY250 3.3 27.1 1.0 CA A:GLY250 3.9 27.5 1.0 O A:HOH1348 4.0 27.4 1.0 N A:LEU251 4.3 23.8 1.0 O A:ILE295 4.6 22.0 1.0 CA A:LEU251 4.6 25.1 1.0 CA A:ILE296 4.7 21.2 1.0 O A:HOH1570 4.7 17.8 1.0 O A:HOH1353 4.8 26.3 1.0 CD2 A:HIS297 4.8 27.1 1.0

A.K.Marapaka, A.Addlagatta. Crystal Structure of Plasmodium Falciparum Aminopeptidase N in Complex with (S)-2-((2S,3R)-3-Amino-2-Hydroxy-4-Phenylbutanamido)- N-Hydroxy-4-Methylpentanamide. To Be Published.