Magnesium in PDB 5y8h: Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+

All present enzymatic activity of Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+:
1.1.1.31;

The structure of Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+, PDB code: 5y8h was solved by R.Srikalaivani, A.Singh, A.Surolia, M.Vijayan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	112.09 / 2.10
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	129.430, 129.430, 70.490, 90.00, 90.00, 120.00
R / Rfree (%)	15.9 / 21.1

The binding sites of Magnesium atom in the Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+ (pdb code 5y8h). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+, PDB code: 5y8h:

Magnesium binding site 1 out of 1 in the Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mycobacterium Tuberculosis 3-Hydroxyisobutyrate Dehydrogenase (Mthibadh) + Nad+ within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg303 b:33.7 occ:1.00 O A:HOH621 2.9 40.1 1.0 OG1 A:THR97 3.0 30.4 1.0 O A:HOH575 3.2 48.9 1.0 N A:THR97 3.4 22.9 1.0 N A:VAL96 3.7 22.7 1.0 O A:HOH595 3.8 33.7 1.0 CB A:THR97 3.8 27.8 1.0 CB A:SER95 3.8 22.0 1.0 CA A:ALA251 3.9 23.0 1.0 CB A:VAL96 4.0 23.0 1.0 CB A:ALA254 4.2 32.0 1.0 CA A:THR97 4.2 25.0 1.0 CB A:ALA251 4.2 24.2 1.0 CA A:VAL96 4.2 23.0 1.0 N A:ALA251 4.2 25.1 1.0 OG A:SER95 4.2 21.2 1.0 C A:VAL96 4.3 23.8 1.0 C A:SER95 4.4 21.8 1.0 O A:ASP250 4.5 29.4 1.0 C A:ASP250 4.5 26.6 1.0 CA A:SER95 4.6 20.7 1.0 O A:HOH484 4.6 29.4 1.0 CG2 A:VAL96 4.7 24.8 1.0 CD2 B:LEU192 4.8 20.9 1.0

R.Srikalaivani, A.Singh, M.Vijayan, A.Surolia. Structure, Interactions and Action Ofmycobacterium TUBERCULOSIS3-Hydroxyisobutyric Acid Dehydrogenase. Biochem. J. V. 475 2457 2018.
ISSN: ESSN 1470-8728
PubMed: 29959185
DOI: 10.1042/BCJ20180271