Magnesium in PDB 5z58: Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
Enzymatic activity of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
All present enzymatic activity of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.:
3.6.4.13;
5.2.1.8;
Other elements in 5z58:
The structure of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
(pdb code 5z58). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the
Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom., PDB code: 5z58:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
Magnesium binding site 1 out
of 6 in 5z58
Go back to
Magnesium Binding Sites List in 5z58
Magnesium binding site 1 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg1501
b:40.6
occ:1.00
|
O1G
|
C:GTP1500
|
1.8
|
0.5
|
1.0
|
OG1
|
C:THR143
|
1.9
|
78.9
|
1.0
|
O2B
|
C:GTP1500
|
2.1
|
81.2
|
1.0
|
PG
|
C:GTP1500
|
3.2
|
0.7
|
1.0
|
CB
|
C:THR143
|
3.2
|
69.7
|
1.0
|
PB
|
C:GTP1500
|
3.3
|
68.0
|
1.0
|
O3B
|
C:GTP1500
|
3.7
|
90.2
|
1.0
|
CG2
|
C:THR143
|
3.9
|
66.8
|
1.0
|
O1B
|
C:GTP1500
|
4.0
|
61.5
|
1.0
|
O2G
|
C:GTP1500
|
4.0
|
0.9
|
1.0
|
O3G
|
C:GTP1500
|
4.2
|
0.7
|
1.0
|
CA
|
C:THR143
|
4.3
|
63.5
|
1.0
|
N
|
C:THR143
|
4.4
|
59.5
|
1.0
|
O3A
|
C:GTP1500
|
4.5
|
59.5
|
1.0
|
O2A
|
C:GTP1500
|
4.5
|
60.4
|
1.0
|
O1A
|
C:GTP1500
|
4.7
|
52.8
|
1.0
|
PA
|
C:GTP1500
|
4.8
|
53.9
|
1.0
|
OD2
|
C:ASP204
|
4.9
|
0.5
|
1.0
|
OD1
|
C:ASP204
|
4.9
|
0.0
|
1.0
|
|
Magnesium binding site 2 out
of 6 in 5z58
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Magnesium Binding Sites List in 5z58
Magnesium binding site 2 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg200
b:0.6
occ:1.00
|
OP2
|
F:U74
|
2.1
|
0.2
|
1.0
|
OP1
|
F:G72
|
2.4
|
0.6
|
1.0
|
P
|
F:U74
|
3.3
|
0.3
|
1.0
|
OP1
|
F:U74
|
3.6
|
0.7
|
1.0
|
O2'
|
G:G-1
|
3.8
|
0.6
|
1.0
|
P
|
F:G72
|
3.9
|
0.9
|
1.0
|
O3'
|
G:G-1
|
3.9
|
0.2
|
1.0
|
O3'
|
F:A73
|
4.3
|
0.3
|
1.0
|
OP1
|
F:G54
|
4.3
|
0.7
|
1.0
|
O5'
|
F:U74
|
4.4
|
0.2
|
1.0
|
C3'
|
F:A73
|
4.5
|
0.6
|
1.0
|
O5'
|
F:G72
|
4.5
|
0.0
|
1.0
|
C3'
|
G:G-1
|
4.7
|
0.6
|
1.0
|
C4'
|
G:G-1
|
4.7
|
0.5
|
1.0
|
OP2
|
F:G72
|
4.8
|
0.1
|
1.0
|
O3'
|
F:G71
|
4.8
|
0.9
|
1.0
|
C4'
|
F:A73
|
4.8
|
0.3
|
1.0
|
O5'
|
F:G54
|
4.8
|
0.3
|
1.0
|
C2'
|
G:G-1
|
4.8
|
0.1
|
1.0
|
C5'
|
F:G72
|
4.9
|
0.8
|
1.0
|
C5'
|
F:A73
|
4.9
|
0.8
|
1.0
|
C5'
|
F:U74
|
4.9
|
0.2
|
1.0
|
P
|
F:G54
|
4.9
|
0.3
|
1.0
|
OP2
|
G:G1
|
5.0
|
0.9
|
1.0
|
|
Magnesium binding site 3 out
of 6 in 5z58
Go back to
Magnesium Binding Sites List in 5z58
Magnesium binding site 3 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg201
b:0.0
occ:1.00
|
OP2
|
F:G54
|
1.9
|
0.4
|
1.0
|
OP1
|
F:A53
|
2.0
|
0.8
|
1.0
|
OP1
|
F:U74
|
2.1
|
0.7
|
1.0
|
P
|
F:A53
|
2.4
|
0.2
|
1.0
|
OP2
|
F:A53
|
2.7
|
1.0
|
1.0
|
O5'
|
F:A53
|
2.8
|
0.1
|
1.0
|
P
|
F:G54
|
3.2
|
0.3
|
1.0
|
P
|
F:U74
|
3.6
|
0.3
|
1.0
|
OP1
|
F:G54
|
3.6
|
0.7
|
1.0
|
C5'
|
F:A53
|
3.8
|
0.3
|
1.0
|
O3'
|
F:U52
|
4.0
|
0.9
|
1.0
|
O3'
|
F:A53
|
4.2
|
1.0
|
1.0
|
O5'
|
F:U74
|
4.2
|
0.2
|
1.0
|
O5'
|
F:G54
|
4.2
|
0.3
|
1.0
|
C3'
|
F:A53
|
4.4
|
97.1
|
1.0
|
O3'
|
F:A73
|
4.4
|
0.3
|
1.0
|
OP2
|
F:U74
|
4.5
|
0.2
|
1.0
|
C5'
|
F:G54
|
4.5
|
0.8
|
1.0
|
C4'
|
F:A53
|
4.7
|
91.4
|
1.0
|
C3'
|
F:U52
|
5.0
|
0.4
|
1.0
|
|
Magnesium binding site 4 out
of 6 in 5z58
Go back to
Magnesium Binding Sites List in 5z58
Magnesium binding site 4 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg202
b:97.8
occ:1.00
|
OP1
|
F:G75
|
2.6
|
0.1
|
1.0
|
P
|
F:G75
|
3.9
|
0.4
|
1.0
|
O5'
|
F:G75
|
4.2
|
0.3
|
1.0
|
O4
|
F:U57
|
4.3
|
0.2
|
1.0
|
N4
|
F:C77
|
4.3
|
0.3
|
1.0
|
OP2
|
F:A76
|
4.4
|
0.4
|
1.0
|
N7
|
F:G75
|
4.4
|
0.5
|
1.0
|
N7
|
F:A76
|
4.4
|
0.6
|
1.0
|
C8
|
F:G75
|
4.7
|
0.8
|
1.0
|
C2'
|
F:U74
|
4.8
|
0.0
|
1.0
|
OP2
|
F:G75
|
4.9
|
0.3
|
1.0
|
O3'
|
F:U74
|
4.9
|
0.5
|
1.0
|
|
Magnesium binding site 5 out
of 6 in 5z58
Go back to
Magnesium Binding Sites List in 5z58
Magnesium binding site 5 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg203
b:0.8
occ:1.00
|
OP2
|
F:G75
|
2.1
|
0.3
|
1.0
|
P
|
F:G75
|
3.3
|
0.4
|
1.0
|
OP1
|
F:G75
|
3.9
|
0.1
|
1.0
|
O3'
|
F:U74
|
3.9
|
0.5
|
1.0
|
OP2
|
F:G72
|
4.2
|
0.1
|
1.0
|
OP2
|
F:G71
|
4.4
|
0.4
|
1.0
|
N7
|
F:G72
|
4.5
|
0.4
|
1.0
|
OP2
|
F:A56
|
4.5
|
0.4
|
1.0
|
O5'
|
F:G75
|
4.6
|
0.3
|
1.0
|
N7
|
F:G71
|
4.8
|
0.2
|
1.0
|
C8
|
F:G71
|
4.9
|
0.5
|
1.0
|
C5'
|
F:G75
|
5.0
|
0.4
|
1.0
|
|
Magnesium binding site 6 out
of 6 in 5z58
Go back to
Magnesium Binding Sites List in 5z58
Magnesium binding site 6 out
of 6 in the Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom.
 Mono view
 Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Cryo-Em Structure of A Human Activated Spliceosome (Early Bact) at 4.9 Angstrom. within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg204
b:0.7
occ:1.00
|
OP1
|
F:C55
|
2.1
|
0.8
|
1.0
|
OP1
|
F:G71
|
2.1
|
0.3
|
1.0
|
P
|
F:C55
|
3.2
|
0.3
|
1.0
|
P
|
F:G71
|
3.5
|
0.6
|
1.0
|
O5'
|
F:C55
|
3.6
|
0.8
|
1.0
|
O3'
|
F:G54
|
3.7
|
0.5
|
1.0
|
NE2
|
A:GLN675
|
3.9
|
60.0
|
1.0
|
C5'
|
F:C55
|
4.0
|
98.2
|
1.0
|
O5'
|
F:G71
|
4.1
|
1.0
|
1.0
|
OP2
|
F:G71
|
4.3
|
0.4
|
1.0
|
C5'
|
F:G71
|
4.5
|
0.1
|
1.0
|
OP2
|
F:C55
|
4.6
|
0.9
|
1.0
|
O3'
|
F:A70
|
4.6
|
0.2
|
1.0
|
|
Reference:
X.Zhang,
C.Yan,
X.Zhan,
L.Li,
J.Lei,
Y.Shi.
Structure of the Human Activated Spliceosome in Three Conformational States. Cell Res. V. 28 307 2018.
ISSN: ISSN 1748-7838
PubMed: 29360106
DOI: 10.1038/CR.2018.14
Page generated: Mon Sep 30 11:44:26 2024
|