Magnesium in PDB 5zc9: Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex

All present enzymatic activity of Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex:
3.6.4.13;

The structure of Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex, PDB code: 5zc9 was solved by W.Iwasaki, M.Takahashi, A.Sakamoto, S.Iwasaki, T.Ito, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.73 / 2.00
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	68.508, 100.263, 155.422, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 23.1

The binding sites of Magnesium atom in the Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex (pdb code 5zc9). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex, PDB code: 5zc9:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human EIF4A1-Atp Analog-Roca-Polypurine Rna Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:26.0 occ:1.00 O3G A:ANP500 1.9 28.8 1.0 O1B A:ANP500 2.1 27.1 1.0 O A:HOH629 2.2 19.9 1.0 O A:HOH673 2.2 23.5 1.0 O A:HOH613 2.2 23.8 1.0 O A:HOH618 2.3 23.9 1.0 PG A:ANP500 3.2 28.2 1.0 PB A:ANP500 3.2 25.5 1.0 N3B A:ANP500 3.5 27.5 1.0 OG1 A:THR83 3.8 29.7 1.0 OE2 A:GLU183 3.8 23.1 1.0 OD2 A:ASP182 3.8 23.4 1.0 CA A:GLY335 4.1 20.4 1.0 OD1 A:ASP182 4.1 20.6 1.0 O2G A:ANP500 4.2 25.3 1.0 O1G A:ANP500 4.2 29.7 1.0 O1A A:ANP500 4.2 26.1 1.0 O2B A:ANP500 4.3 25.2 1.0 O3A A:ANP500 4.3 25.2 1.0 CE A:LYS82 4.4 28.1 1.0 CG A:ASP182 4.4 26.9 1.0 O A:HOH702 4.5 21.4 1.0 O A:GLY335 4.5 26.1 1.0 CB A:LYS82 4.5 28.0 1.0 PA A:ANP500 4.6 26.9 1.0 O2A A:ANP500 4.6 27.1 1.0 N A:THR83 4.7 24.1 1.0 C A:GLY335 4.8 21.3 1.0 CD A:GLU183 4.9 27.2 1.0 NZ A:LYS82 4.9 23.1 1.0 O A:HOH660 5.0 21.6 1.0

S.Iwasaki, W.Iwasaki, M.Takahashi, A.Sakamoto, C.Watanabe, Y.Shichino, S.N.Floor, K.Fujiwara, M.Mito, K.Dodo, M.Sodeoka, H.Imataka, T.Honma, K.Fukuzawa, T.Ito, N.T.Ingolia. The Translation Inhibitor Rocaglamide Targets A Bimolecular Cavity Between EIF4A and Polypurine Rna. Mol. Cell V. 73 738 2019.
ISSN: ISSN 1097-4164
PubMed: 30595437
DOI: 10.1016/J.MOLCEL.2018.11.026