Magnesium in PDB 6au6: Crystal Structure of Gdp-Bound Human Gnas R201C Mutant

The structure of Crystal Structure of Gdp-Bound Human Gnas R201C Mutant, PDB code: 6au6 was solved by Q.Hu, K.M.Shokat, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.04 / 1.70
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.370, 85.580, 125.640, 90.00, 90.00, 90.00
R / Rfree (%)	16.8 / 20

The structure of Crystal Structure of Gdp-Bound Human Gnas R201C Mutant also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Magnesium atom in the Crystal Structure of Gdp-Bound Human Gnas R201C Mutant (pdb code 6au6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Gdp-Bound Human Gnas R201C Mutant, PDB code: 6au6:

Magnesium binding site 1 out of 1 in the Crystal Structure of Gdp-Bound Human Gnas R201C Mutant


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Gdp-Bound Human Gnas R201C Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:13.4 occ:1.00 O1B A:GDP401 2.0 13.3 1.0 O A:HOH522 2.1 12.7 1.0 O A:HOH574 2.1 13.1 1.0 OG A:SER54 2.1 13.5 1.0 O A:HOH599 2.1 14.6 1.0 O A:HOH551 2.1 14.8 1.0 CB A:SER54 3.1 13.1 1.0 PB A:GDP401 3.3 13.1 1.0 O3B A:GDP401 3.5 13.8 1.0 OD2 A:ASP223 4.0 16.2 1.0 O A:HOH560 4.0 17.5 1.0 O1A A:GDP401 4.0 13.3 1.0 N A:SER54 4.1 12.0 1.0 O A:HOH716 4.1 24.0 1.0 CA A:SER54 4.2 12.7 1.0 O3A A:GDP401 4.2 12.0 1.0 OD1 A:ASP223 4.2 17.0 1.0 O A:THR204 4.4 17.2 1.0 O A:HOH570 4.4 20.1 1.0 O2B A:GDP401 4.4 12.6 1.0 O A:VAL202 4.4 17.9 1.0 O A:HOH578 4.4 21.6 1.0 PA A:GDP401 4.5 13.9 1.0 CG A:ASP223 4.5 13.4 1.0 O2A A:GDP401 4.7 14.2 1.0 CA A:LEU203 4.8 18.2 1.0 N A:THR204 4.9 17.5 1.0 CD2 A:LEU203 4.9 19.8 1.0

Q.Hu, K.M.Shokat. Disease-Causing Mutations in the G Protein G Alpha S Subvert the Roles of Gdp and Gtp. Cell V. 173 1254 2018.
ISSN: ISSN 1097-4172
PubMed: 29628140
DOI: 10.1016/J.CELL.2018.03.018