Magnesium in PDB 6b8p: Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex

The structure of Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex, PDB code: 6b8p was solved by A.Chang, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.96 / 2.20
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	108.141, 142.875, 164.082, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 24

The binding sites of Magnesium atom in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex (pdb code 6b8p). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex, PDB code: 6b8p:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg201 b:43.9 occ:1.00 OE1 B:GLU31 2.1 68.3 1.0 OD1 B:ASP24 2.2 72.1 1.0 O B:HOH327 2.4 30.0 1.0 O B:THR26 2.6 50.3 1.0 OD1 B:ASP22 2.7 75.8 1.0 OD1 B:ASP20 2.7 49.9 1.0 CD B:GLU31 2.8 65.0 1.0 OE2 B:GLU31 2.9 77.2 1.0 CG B:ASP24 3.1 66.9 1.0 CG B:ASP22 3.5 79.9 1.0 OD2 B:ASP22 3.5 81.9 1.0 OD2 B:ASP24 3.5 88.6 1.0 C B:THR26 3.7 47.0 1.0 OG1 B:THR26 3.8 60.2 1.0 CG B:ASP20 3.8 49.6 1.0 N B:THR26 4.2 47.1 1.0 CG B:GLU31 4.2 49.3 1.0 CA B:ASP20 4.2 45.3 1.0 CB B:ASP24 4.4 61.3 1.0 CA B:THR26 4.4 44.8 1.0 N B:ASP24 4.4 42.3 1.0 CB B:ASP20 4.4 48.9 1.0 N B:ILE27 4.7 45.7 1.0 OD2 B:ASP20 4.7 48.0 1.0 CB B:THR26 4.7 49.9 1.0 C B:ASP20 4.8 49.2 1.0 CA B:ASP24 4.8 54.2 1.0 CA B:ILE27 4.9 42.7 1.0 CB B:ASP22 4.9 54.4 1.0 N B:ASP22 4.9 61.4 1.0 N B:LYS21 4.9 56.7 1.0 N B:GLY25 4.9 48.3 1.0 N B:GLY23 5.0 55.0 1.0 C B:ASP24 5.0 47.1 1.0

Magnesium binding site 2 out of 4 in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg201 b:41.3 occ:1.00 OE2 D:GLU31 2.1 62.7 1.0 OD2 D:ASP24 2.2 71.3 1.0 O D:HOH327 2.4 30.0 1.0 O D:THR26 2.5 44.5 1.0 OD1 D:ASP20 2.5 44.8 1.0 OD1 D:ASP22 2.6 73.5 1.0 OE1 D:GLU31 2.7 62.6 1.0 CD D:GLU31 2.7 60.4 1.0 CG D:ASP24 3.1 56.2 1.0 CG D:ASP22 3.4 71.3 1.0 OD2 D:ASP22 3.5 64.2 1.0 C D:THR26 3.6 49.9 1.0 OD1 D:ASP24 3.7 67.7 1.0 CG D:ASP20 3.7 50.4 1.0 OG1 D:THR26 3.7 56.7 1.0 N D:THR26 4.1 44.8 1.0 CG D:GLU31 4.2 48.1 1.0 CB D:ASP24 4.3 53.2 1.0 CA D:ASP20 4.3 41.3 1.0 CA D:THR26 4.3 48.5 1.0 CB D:ASP20 4.4 45.5 1.0 N D:ASP24 4.4 52.0 1.0 OD2 D:ASP20 4.6 48.0 1.0 N D:ILE27 4.6 43.4 1.0 CB D:THR26 4.6 47.2 1.0 CA D:ASP24 4.8 51.3 1.0 C D:ASP20 4.8 52.4 1.0 CA D:ILE27 4.8 44.7 1.0 CB D:ASP22 4.8 53.4 1.0 N D:ASP22 4.8 52.5 1.0 N D:GLY25 4.9 47.1 1.0 C D:ASP24 4.9 50.2 1.0 N D:LYS21 4.9 56.9 1.0 N D:GLY23 5.0 56.0 1.0

Magnesium binding site 3 out of 4 in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg201 b:49.3 occ:1.00 OE2 F:GLU31 2.1 64.2 1.0 OD1 F:ASP24 2.4 64.4 1.0 O F:THR26 2.5 54.8 1.0 OD2 F:ASP20 2.6 54.6 1.0 O F:HOH306 2.7 30.0 1.0 OD2 F:ASP22 2.9 77.7 1.0 CD F:GLU31 2.9 75.0 1.0 OE1 F:GLU31 3.1 81.4 1.0 CG F:ASP24 3.1 69.3 1.0 OD2 F:ASP24 3.2 86.0 1.0 OG1 F:THR26 3.6 60.9 1.0 C F:THR26 3.6 57.6 1.0 CG F:ASP20 3.7 58.9 1.0 CG F:ASP22 3.8 82.7 1.0 OD1 F:ASP22 4.0 84.3 1.0 N F:THR26 4.2 50.4 1.0 CA F:ASP20 4.2 50.7 1.0 CA F:THR26 4.3 55.2 1.0 CG F:GLU31 4.4 62.0 1.0 CB F:ASP20 4.4 55.5 1.0 N F:ASP24 4.5 66.0 1.0 CB F:ASP24 4.5 62.2 1.0 CB F:THR26 4.6 61.1 1.0 N F:ILE27 4.6 53.6 1.0 O F:HOH334 4.7 57.3 1.0 OD1 F:ASP20 4.7 54.3 1.0 C F:ASP20 4.8 55.3 1.0 CA F:ILE27 4.8 52.7 1.0 CA F:ASP24 4.9 62.8 1.0 N F:LYS21 4.9 58.4 1.0 CG2 F:THR28 5.0 56.4 1.0 C F:ASP24 5.0 61.5 1.0

Magnesium binding site 4 out of 4 in the Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure of the MG2+/Cam:KV7.4 (KCNQ4) Ab Domain Complex within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg201 b:48.3 occ:1.00 OE2 H:GLU31 2.3 72.5 1.0 OD1 H:ASP24 2.3 78.2 1.0 OD1 H:ASP20 2.5 60.2 1.0 OE1 H:GLU31 2.6 66.3 1.0 O H:THR26 2.7 54.7 1.0 OD1 H:ASP22 2.7 82.8 1.0 CD H:GLU31 2.8 68.4 1.0 OD2 H:ASP22 3.3 81.3 1.0 CG H:ASP24 3.3 68.4 1.0 CG H:ASP22 3.3 86.7 1.0 OG1 H:THR26 3.6 69.9 1.0 CG H:ASP20 3.7 62.8 1.0 C H:THR26 3.7 56.6 1.0 OD2 H:ASP24 3.7 77.8 1.0 CG H:GLU31 4.2 53.9 1.0 N H:THR26 4.3 54.5 1.0 CB H:ASP20 4.4 53.9 1.0 CA H:ASP20 4.4 56.4 1.0 CA H:THR26 4.4 56.5 1.0 CB H:ASP24 4.5 67.0 1.0 CB H:THR26 4.6 57.6 1.0 N H:ASP24 4.6 60.0 1.0 OD2 H:ASP20 4.6 57.3 1.0 N H:ILE27 4.7 55.1 1.0 CB H:ASP22 4.8 74.6 1.0 CA H:ILE27 4.9 52.2 1.0 C H:ASP20 4.9 64.0 1.0 N H:ASP22 4.9 63.0 1.0 CA H:ASP24 5.0 66.5 1.0

A.Chang, F.Abderemane-Ali, G.L.Hura, N.D.Rossen, R.E.Gate, D.L.Minor. A Calmodulin C-Lobe Ca Neuron V. 97 836 2018.
ISSN: ISSN 1097-4199
PubMed: 29429937
DOI: 10.1016/J.NEURON.2018.01.035