Magnesium in PDB 6b9e: Human ATL1 Mutant - R77A / F151S Bound to Gdp

The structure of Human ATL1 Mutant - R77A / F151S Bound to Gdp, PDB code: 6b9e was solved by J.P.O'donnell, H.Sondermann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	13.85 / 1.99
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	52.062, 68.107, 76.016, 116.85, 90.77, 98.50
R / Rfree (%)	20.3 / 24.4

The binding sites of Magnesium atom in the Human ATL1 Mutant - R77A / F151S Bound to Gdp (pdb code 6b9e). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human ATL1 Mutant - R77A / F151S Bound to Gdp, PDB code: 6b9e:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human ATL1 Mutant - R77A / F151S Bound to Gdp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human ATL1 Mutant - R77A / F151S Bound to Gdp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:64.7 occ:1.00 OD1 A:ASP146 2.8 35.1 1.0 O2B A:GDP501 2.9 49.6 1.0 OG A:SER81 3.0 34.0 1.0 NE2 A:GLN148 3.2 50.7 1.0 OD2 A:ASP146 3.3 35.1 1.0 CG A:ASP146 3.3 36.5 1.0 CD A:GLN148 3.5 56.5 1.0 CB A:GLN148 3.7 49.9 1.0 OE1 A:GLN148 3.8 60.6 1.0 PB A:GDP501 4.0 42.7 1.0 CE A:LYS80 4.0 36.8 1.0 CG A:GLN148 4.1 54.4 1.0 CB A:LYS80 4.1 24.1 1.0 O1B A:GDP501 4.1 39.3 1.0 N A:SER81 4.2 26.2 1.0 CB A:SER81 4.3 32.1 1.0 CA A:GLN148 4.3 56.0 1.0 O A:HOH623 4.4 46.7 1.0 NZ A:LYS80 4.4 41.0 1.0 O3B A:GDP501 4.4 46.7 1.0 N A:GLN148 4.6 58.9 1.0 CA A:SER81 4.7 29.2 1.0 O A:THR147 4.7 49.6 1.0 C A:THR147 4.7 52.1 1.0 CB A:ASP146 4.7 32.3 1.0 CD A:LYS80 4.9 33.9 1.0 C A:LYS80 4.9 22.7 1.0 CG A:LYS80 4.9 29.6 1.0 N A:THR147 4.9 32.9 1.0

Magnesium binding site 2 out of 2 in the Human ATL1 Mutant - R77A / F151S Bound to Gdp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human ATL1 Mutant - R77A / F151S Bound to Gdp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg503 b:60.1 occ:1.00 OD1 B:ASP146 2.8 32.3 1.0 O2B B:GDP502 2.9 51.2 1.0 OG B:SER81 3.0 39.0 1.0 NE2 B:GLN148 3.1 41.5 1.0 OD2 B:ASP146 3.2 29.4 1.0 CG B:ASP146 3.3 33.4 1.0 CD B:GLN148 3.4 52.1 1.0 OE1 B:GLN148 3.8 56.8 1.0 CB B:GLN148 3.9 49.1 1.0 O3B B:GDP502 4.0 37.0 1.0 PB B:GDP502 4.0 41.0 1.0 CG B:GLN148 4.1 54.7 1.0 NZ B:LYS80 4.1 47.0 1.0 CB B:SER81 4.3 40.0 1.0 N B:SER81 4.3 34.3 1.0 CB B:LYS80 4.4 25.5 1.0 CE B:LYS80 4.5 41.8 1.0 CA B:GLN148 4.5 48.2 1.0 O1B B:GDP502 4.6 38.7 1.0 CA B:SER81 4.7 44.0 1.0 CB B:ASP146 4.8 27.5 1.0 N B:GLN148 4.9 47.0 1.0

J.P.O'donnell, L.J.Byrnes, R.B.Cooley, H.Sondermann. A Hereditary Spastic Paraplegia-Associated Atlastin Variant Exhibits Defective Allosteric Coupling in the Catalytic Core. J. Biol. Chem. V. 293 687 2018.
ISSN: ESSN 1083-351X
PubMed: 29180453
DOI: 10.1074/JBC.RA117.000380