Magnesium in PDB 6bc0: A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog

The structure of A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog, PDB code: 6bc0 was solved by Z.Chen, P.C.Sternweis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.61 / 2.20
Space group	P 65 2 2
Cell size a, b, c (Å), α, β, γ (°)	73.160, 73.160, 266.270, 90.00, 90.00, 120.00
R / Rfree (%)	22.3 / 28.1

The binding sites of Magnesium atom in the A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog (pdb code 6bc0). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog, PDB code: 6bc0:

Magnesium binding site 1 out of 1 in the A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of A Complex Between pH Domain of P190RHOGEF and Activated Rhoa Bound to A Gtp Analog within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg201 b:82.0 occ:1.00 HOG2 F:GSP202 1.5 74.5 1.0 HG1 F:THR37 1.5 88.1 1.0 O2B F:GSP202 1.9 73.0 1.0 O F:HOH310 1.9 58.4 1.0 OG1 F:THR19 1.9 76.5 1.0 OG1 F:THR37 2.0 73.4 1.0 O F:HOH313 2.3 70.5 1.0 O2G F:GSP202 2.3 62.1 1.0 HB F:THR19 2.9 85.3 1.0 CB F:THR19 3.0 71.1 1.0 PB F:GSP202 3.1 78.6 1.0 CB F:THR37 3.2 79.6 1.0 HB F:THR37 3.2 95.5 1.0 H F:THR19 3.3 88.3 1.0 PG F:GSP202 3.4 78.7 1.0 O3B F:GSP202 3.5 60.2 1.0 H F:THR37 3.7 99.2 1.0 N F:THR19 3.9 73.6 1.0 HG21 F:THR37 3.9 94.8 1.0 HG21 F:THR19 3.9 94.3 1.0 CA F:THR19 4.0 71.4 1.0 OD1 F:ASP59 4.0 67.7 1.0 OD2 F:ASP59 4.0 73.5 1.0 CG2 F:THR19 4.0 78.6 1.0 CG2 F:THR37 4.1 79.0 1.0 HB2 F:LYS18 4.1 72.7 1.0 N F:THR37 4.1 82.7 1.0 O3G F:GSP202 4.1 65.8 1.0 O2A F:GSP202 4.2 73.1 1.0 O3A F:GSP202 4.2 61.4 1.0 O1B F:GSP202 4.2 64.8 1.0 CA F:THR37 4.2 65.9 1.0 HA F:THR19 4.3 85.7 1.0 HE2 F:LYS18 4.4 77.3 1.0 CG F:ASP59 4.4 68.3 1.0 HG23 F:THR37 4.4 94.8 1.0 HG23 F:THR19 4.4 94.3 1.0 HOG3 F:GSP202 4.5 79.0 1.0 PA F:GSP202 4.5 79.5 1.0 O F:THR60 4.5 58.5 1.0 HA F:PRO36 4.6 0.5 1.0 O F:VAL35 4.6 81.4 1.0 HE1 F:TYR34 4.7 0.8 1.0 HA F:THR37 4.7 79.1 1.0 O1A F:GSP202 4.7 80.3 1.0 HZ1 F:LYS18 4.7 88.0 1.0 HG22 F:THR19 4.8 94.3 1.0 S1G F:GSP202 4.9 92.2 1.0 HZ3 F:LYS18 4.9 88.0 1.0 HG22 F:THR37 4.9 94.8 1.0 C F:PRO36 5.0 89.0 1.0 C F:LYS18 5.0 70.7 1.0 CB F:LYS18 5.0 60.5 1.0

O.Dada, S.Gutowski, C.A.Brautigam, Z.Chen, P.C.Sternweis. Direct Regulation of P190RHOGEF By Activated Rho and Rac Gtpases. J. Struct. Biol. V. 202 13 2018.
ISSN: ESSN 1095-8657
PubMed: 29196061
DOI: 10.1016/J.JSB.2017.11.014