Magnesium in PDB 6bhu: Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1)

The binding sites of Magnesium atom in the Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1) (pdb code 6bhu). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1), PDB code: 6bhu:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1603 b:0.3 occ:1.00 O1G A:ATP1601 2.0 0.8 1.0 O1B A:ATP1601 2.0 0.4 1.0 OE1 A:GLN713 2.0 0.2 1.0 OG A:SER685 2.0 1.0 1.0 CD A:GLN713 2.9 0.3 1.0 NE2 A:GLN713 3.1 0.9 1.0 CB A:SER685 3.2 0.4 1.0 PB A:ATP1601 3.3 0.3 1.0 PG A:ATP1601 3.4 0.2 1.0 OD1 A:ASP792 3.7 0.1 1.0 O3B A:ATP1601 3.8 0.3 1.0 O2B A:ATP1601 4.2 0.4 1.0 O3G A:ATP1601 4.3 0.7 1.0 N A:SER685 4.3 0.8 1.0 CA A:SER685 4.3 0.7 1.0 CG A:GLN713 4.3 1.0 1.0 O2G A:ATP1601 4.4 0.6 1.0 O2A A:ATP1601 4.5 0.7 1.0 O3A A:ATP1601 4.5 0.1 1.0 OD2 A:ASP792 4.5 0.1 1.0 CG A:ASP792 4.5 0.7 1.0 O1A A:ATP1601 4.8 0.6 1.0 PA A:ATP1601 4.8 0.4 1.0 CB A:GLN713 4.8 0.3 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of Atp-Bound, Outward-Facing Bovine Multidrug Resistance Protein 1 (MRP1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1604 b:0.5 occ:1.00 OG A:SER1333 1.9 0.6 1.0 OE1 A:GLN1374 2.1 0.1 1.0 O2B A:ATP1602 2.1 0.1 1.0 O2G A:ATP1602 2.2 0.9 1.0 CD A:GLN1374 3.0 0.4 1.0 CB A:SER1333 3.1 0.4 1.0 NE2 A:GLN1374 3.2 1.0 1.0 PB A:ATP1602 3.3 0.8 1.0 PG A:ATP1602 3.3 0.5 1.0 O3G A:ATP1602 3.7 0.3 1.0 O3B A:ATP1602 3.8 0.9 1.0 O1B A:ATP1602 4.0 0.9 1.0 OD1 A:ASP1453 4.0 0.3 1.0 N A:SER1333 4.2 0.2 1.0 CA A:SER1333 4.2 0.0 1.0 CG A:GLN1374 4.4 0.4 1.0 OD2 A:ASP1453 4.5 0.4 1.0 O3A A:ATP1602 4.6 0.1 1.0 O1G A:ATP1602 4.6 0.6 1.0 O1A A:ATP1602 4.7 0.4 1.0 CG A:ASP1453 4.7 0.6 1.0 CB A:GLN1374 4.9 0.2 1.0 OE1 A:GLN1454 4.9 0.3 1.0 O2A A:ATP1602 5.0 0.8 1.0 PA A:ATP1602 5.0 0.5 1.0

Z.L.Johnson, J.Chen. Atp Binding Enables Substrate Release From Multidrug Resistance Protein 1. Cell V. 172 81 2018.
ISSN: ISSN 1097-4172
PubMed: 29290467
DOI: 10.1016/J.CELL.2017.12.005