Magnesium in PDB 6bwd: 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7

The binding sites of Magnesium atom in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 (pdb code 6bwd). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7, PDB code: 6bwd:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1201 b:32.7 occ:1.00 O B:HOH1301 2.0 24.8 1.0 O A:HOH1304 2.0 25.6 1.0 O C:HOH1404 2.1 26.8 1.0 O D:HOH1303 2.1 26.7 1.0 O D:HOH1308 2.1 27.3 1.0 O D:HOH1305 2.1 25.9 1.0 OE1 A:GLU885 3.5 33.1 1.0 O A:HOH1301 3.5 29.6 1.0 OE1 B:GLU885 3.6 37.6 1.0 OE1 D:GLU885 3.8 32.1 1.0 O B:HOH1302 4.0 27.0 1.0 O D:HOH1301 4.1 24.7 1.0 O C:HOH1401 4.1 27.4 1.0 OE1 C:GLU702 4.3 32.5 1.0 O D:GLY884 4.3 31.6 1.0 O A:GLY884 4.4 31.5 1.0 CD A:GLU885 4.4 33.1 1.0 MG B:MG1201 4.5 35.3 1.0 CD B:GLU885 4.5 37.6 1.0 CD D:GLU885 4.6 32.1 1.0 OE2 A:GLU885 4.6 33.1 1.0 O B:GLY884 4.7 36.8 1.0 OE2 D:GLU885 4.8 32.1 1.0 OE2 B:GLU885 4.8 37.6 1.0 O C:GLY701 4.8 29.5 1.0

Magnesium binding site 2 out of 5 in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1202 b:0.1 occ:1.00 O B:HOH1304 2.1 22.8 1.0 O D:HOH1304 2.1 24.2 1.0 O C:HOH1405 2.1 18.1 1.0 O A:HOH1302 2.1 21.6 1.0 O C:HOH1402 3.0 21.6 1.0 OH C:TYR740 3.6 29.1 1.0 OH D:TYR923 3.7 19.8 1.0 OH B:TYR923 3.7 32.0 1.0 OH A:TYR923 3.8 20.6 1.0 CZ D:TYR923 4.7 19.8 1.0 CZ C:TYR740 4.7 29.1 1.0 CZ B:TYR923 4.7 32.0 1.0 CZ A:TYR923 4.8 20.6 1.0

Magnesium binding site 3 out of 5 in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1201 b:35.3 occ:1.00 O D:HOH1308 2.5 27.3 1.0 O D:HOH1301 3.0 24.7 1.0 O B:HOH1302 3.1 27.0 1.0 O A:HOH1301 3.1 29.6 1.0 O C:HOH1401 3.3 27.4 1.0 O A:HOH1306 4.3 44.5 1.0 O C:HOH1407 4.4 34.7 1.0 O C:HOH1406 4.5 30.3 1.0 MG A:MG1201 4.5 32.7 1.0 O A:HOH1305 4.6 32.7 1.0 O A:HOH1304 5.0 25.6 1.0

Magnesium binding site 4 out of 5 in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1202 b:10.8 occ:1.00 O D:HOH1309 2.1 2.6 1.0 O B:HOH1306 2.1 2.8 1.0 O D:HOH1302 2.1 2.5 1.0 O B:HOH1303 2.1 2.8 1.0 O C:HOH1403 2.1 2.5 1.0 O A:HOH1303 2.1 2.8 1.0 O A:HOH1307 3.9 3.4 1.0 O C:HOH1408 4.1 2.5 1.0 O B:HOH1305 4.2 3.3 1.0 ND2 B:ASN935 4.3 24.3 1.0 O D:HOH1306 4.3 3.1 1.0 ND2 D:ASN935 4.5 18.1 1.0 ND2 C:ASN752 4.6 18.6 1.0 ND2 A:ASN935 4.6 17.5 1.0 CG B:ASN935 4.7 24.3 1.0 O B:ASN935 4.8 24.3 1.0 OD1 B:ASN935 4.9 24.3 1.0 CG D:ASN935 5.0 18.1 1.0

Magnesium binding site 5 out of 5 in the 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of 3.7 Angstrom Cryoem Structure of Truncated Mouse TRPM7 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1201 b:0.4 occ:1.00 O D:HOH1307 1.3 10.2 1.0 O C:HOH1402 2.4 21.6 1.0 O B:PHE883 3.6 34.2 1.0 O D:PHE883 3.9 27.9 1.0 OH D:TYR923 4.0 19.8 1.0 OH A:TYR923 4.0 20.6 1.0 OH C:TYR740 4.0 29.1 1.0 O C:PHE700 4.1 31.1 1.0 O A:PHE883 4.1 27.7 1.0 OH B:TYR923 4.1 32.0 1.0 CA B:GLY884 4.5 36.8 1.0 C B:PHE883 4.7 34.2 1.0 CA D:GLY884 4.7 31.6 1.0 CA C:GLY701 4.8 29.5 1.0 CA A:GLY884 4.8 31.5 1.0 CZ D:TYR923 4.9 19.8 1.0 C D:PHE883 4.9 27.9 1.0 CZ A:TYR923 4.9 20.6 1.0 CZ C:TYR740 4.9 29.1 1.0 CZ B:TYR923 5.0 32.0 1.0 CE1 D:TYR923 5.0 19.8 1.0

J.Duan, Z.Li, J.Li, R.E.Hulse, A.Santa-Cruz, W.C.Valinsky, S.A.Abiria, G.Krapivinsky, J.Zhang, D.E.Clapham. Structure of the Mammalian TRPM7, A Magnesium Channel Required During Embryonic Development. Proc. Natl. Acad. Sci. V. 115 E8201 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30108148
DOI: 10.1073/PNAS.1810719115