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Magnesium in PDB 6cer: Human Pyruvate Dehydrogenase Complex E1 Component V138M MutationEnzymatic activity of Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation
All present enzymatic activity of Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation:
1.2.4.1; Protein crystallography data
The structure of Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation, PDB code: 6cer
was solved by
M.J.Whitley,
P.Arjunan,
W.Furey,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation
(pdb code 6cer). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation, PDB code: 6cer: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6cerGo back to Magnesium Binding Sites List in 6cer
Magnesium binding site 1 out
of 2 in the Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6cerGo back to Magnesium Binding Sites List in 6cer
Magnesium binding site 2 out
of 2 in the Human Pyruvate Dehydrogenase Complex E1 Component V138M Mutation
Mono view Stereo pair view
Reference:
M.J.Whitley,
P.Arjunan,
N.S.Nemeria,
L.G.Korotchkina,
Y.H.Park,
M.S.Patel,
F.Jordan,
W.Furey.
Pyruvate Dehydrogenase Complex Deficiency Is Linked to Regulatory Loop Disorder in the Alpha V138M Variant of Human Pyruvate Dehydrogenase. J. Biol. Chem. V. 293 13204 2018.
Page generated: Mon Dec 14 22:29:46 2020
ISSN: ESSN 1083-351X PubMed: 29970614 DOI: 10.1074/JBC.RA118.003996 |
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