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Magnesium in PDB 6cgf: Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2Enzymatic activity of Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2
All present enzymatic activity of Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2:
2.7.7.49; 2.7.7.7; 3.1.13.2; 3.1.26.13; Protein crystallography data
The structure of Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2, PDB code: 6cgf
was solved by
Y.Yang,
L.A.Nguyen,
Z.B.Smithline,
T.A.Steitz,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6cgf:
The structure of Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2
(pdb code 6cgf). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2, PDB code: 6cgf: Magnesium binding site 1 out of 1 in 6cgfGo back to Magnesium Binding Sites List in 6cgf
Magnesium binding site 1 out
of 1 in the Crystal Structure of Hiv-1 Y188L Mutant Reverse Transcriptase in Complex with Non-Nucleoside Inhibitor K-5A2
Mono view Stereo pair view
Reference:
Y.Yang,
D.Kang,
L.A.Nguyen,
Z.B.Smithline,
C.Pannecouque,
P.Zhan,
X.Liu,
T.A.Steitz.
Structural Basis For Potent and Broad Inhibition of Hiv-1 Rt By Thiophene[3,2-D]Pyrimidine Non-Nucleoside Inhibitors. Elife V. 7 2018.
Page generated: Mon Dec 14 22:29:55 2020
ISSN: ESSN 2050-084X PubMed: 30044217 DOI: 10.7554/ELIFE.36340 |
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