Magnesium in PDB 6cri: Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer

The binding sites of Magnesium atom in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer (pdb code 6cri). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer, PDB code: 6cri:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6;

Magnesium binding site 1 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1002 b:1.0 occ:1.01 O1G C:GTP1001 1.9 1.0 1.0 O2B C:GTP1001 2.2 1.0 1.0 OG1 C:THR31 2.3 1.0 1.0 CG2 C:THR31 2.3 1.0 1.0 O3G C:GTP1001 2.4 1.0 1.0 PG C:GTP1001 2.5 1.0 1.0 OG1 C:THR48 2.7 0.2 1.0 CB C:THR31 2.8 1.0 1.0 CG2 C:THR48 2.9 0.2 1.0 PB C:GTP1001 3.1 1.0 1.0 O3B C:GTP1001 3.2 1.0 1.0 CB C:THR48 3.4 0.2 1.0 O3A C:GTP1001 3.5 1.0 1.0 O2G C:GTP1001 3.9 1.0 1.0 N C:THR31 3.9 1.0 1.0 CA C:THR31 4.0 1.0 1.0 O1A C:GTP1001 4.1 1.0 1.0 N C:THR48 4.1 0.2 1.0 CG2 C:THR45 4.1 1.0 1.0 OD2 C:ASP67 4.2 1.0 1.0 O C:ILE46 4.3 1.0 1.0 PA C:GTP1001 4.3 1.0 1.0 CA C:THR48 4.4 0.2 1.0 O1B C:GTP1001 4.4 1.0 1.0 CG C:LYS30 4.7 1.0 1.0 OD1 C:ASN52 4.7 0.8 1.0 O2A C:GTP1001 4.8 1.0 1.0 CG C:ASP67 4.9 1.0 1.0 OD1 C:ASP67 5.0 1.0 1.0 NZ C:LYS30 5.0 1.0 1.0

Magnesium binding site 2 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg1002 b:0.4 occ:1.00 O2G H:GTP1001 1.9 0.3 1.0 O1B H:GTP1001 2.2 0.3 1.0 CG2 H:THR31 2.3 0.0 1.0 OG1 H:THR31 2.3 0.0 1.0 O1G H:GTP1001 2.4 0.3 1.0 PG H:GTP1001 2.5 0.3 1.0 OG1 H:THR48 2.5 0.3 1.0 CB H:THR31 2.8 0.0 1.0 PB H:GTP1001 3.1 0.3 1.0 CG2 H:THR48 3.1 0.3 1.0 O3B H:GTP1001 3.2 0.3 1.0 CB H:THR48 3.4 0.3 1.0 O3A H:GTP1001 3.5 0.3 1.0 N H:THR31 3.8 0.0 1.0 N H:THR48 3.8 0.3 1.0 O3G H:GTP1001 3.9 0.3 1.0 CA H:THR31 3.9 0.0 1.0 O1A H:GTP1001 4.1 0.3 1.0 O H:ILE46 4.1 0.6 1.0 CA H:THR48 4.2 0.3 1.0 PA H:GTP1001 4.3 0.3 1.0 CG2 H:THR45 4.3 0.0 1.0 O2B H:GTP1001 4.4 0.3 1.0 OD2 H:ASP67 4.5 0.3 1.0 CG H:LYS30 4.5 0.1 1.0 O2A H:GTP1001 4.8 0.3 1.0 C H:LYS30 4.9 0.1 1.0 C H:PRO47 4.9 0.9 1.0 OD1 H:ASN52 5.0 0.3 1.0

Magnesium binding site 3 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ K:Mg1002 b:1.0 occ:1.01 O1G K:GTP1001 1.9 1.0 1.0 O2B K:GTP1001 2.2 1.0 1.0 OG1 K:THR31 2.3 1.0 1.0 CG2 K:THR31 2.3 1.0 1.0 O3G K:GTP1001 2.4 1.0 1.0 PG K:GTP1001 2.5 1.0 1.0 OG1 K:THR48 2.7 0.8 1.0 CB K:THR31 2.8 1.0 1.0 CG2 K:THR48 2.9 0.8 1.0 PB K:GTP1001 3.1 1.0 1.0 O3B K:GTP1001 3.2 1.0 1.0 CB K:THR48 3.4 0.8 1.0 O3A K:GTP1001 3.5 1.0 1.0 O2G K:GTP1001 3.9 1.0 1.0 N K:THR31 3.9 1.0 1.0 CA K:THR31 4.0 1.0 1.0 O1A K:GTP1001 4.1 1.0 1.0 N K:THR48 4.1 0.8 1.0 OD2 K:ASP67 4.1 0.8 1.0 O K:ILE46 4.2 0.3 1.0 PA K:GTP1001 4.3 1.0 1.0 CG2 K:THR45 4.3 0.2 1.0 CA K:THR48 4.4 0.8 1.0 O1B K:GTP1001 4.4 1.0 1.0 OD1 K:ASN52 4.6 0.7 1.0 CG K:LYS30 4.7 1.0 1.0 NZ K:LYS30 4.7 1.0 1.0 O2A K:GTP1001 4.8 1.0 1.0 CG K:ASP67 4.9 0.8 1.0

Magnesium binding site 4 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ U:Mg1002 b:0.7 occ:1.00 O2G U:GTP1001 1.9 0.7 1.0 O1B U:GTP1001 2.2 0.7 1.0 CG2 U:THR31 2.3 0.8 1.0 OG1 U:THR31 2.4 0.8 1.0 O1G U:GTP1001 2.4 0.7 1.0 OG1 U:THR48 2.5 0.6 1.0 PG U:GTP1001 2.5 0.7 1.0 CB U:THR31 2.8 0.8 1.0 CG2 U:THR48 3.1 0.6 1.0 PB U:GTP1001 3.1 0.7 1.0 O3B U:GTP1001 3.2 0.7 1.0 CB U:THR48 3.3 0.6 1.0 O3A U:GTP1001 3.5 0.7 1.0 N U:THR31 3.8 0.8 1.0 N U:THR48 3.8 0.6 1.0 O3G U:GTP1001 3.9 0.7 1.0 CA U:THR31 3.9 0.8 1.0 O U:ILE46 4.0 0.1 1.0 O1A U:GTP1001 4.1 0.7 1.0 CA U:THR48 4.2 0.6 1.0 CG2 U:THR45 4.3 0.7 1.0 PA U:GTP1001 4.3 0.7 1.0 O2B U:GTP1001 4.4 0.7 1.0 CG U:LYS30 4.5 0.0 1.0 OD2 U:ASP67 4.5 0.6 1.0 OD1 U:ASN52 4.7 1.0 1.0 O2A U:GTP1001 4.8 0.7 1.0 C U:PRO47 4.9 0.9 1.0 C U:LYS30 5.0 0.0 1.0

Magnesium binding site 5 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ L:Mg1002 b:1.0 occ:1.01 O1G L:GTP1001 1.9 1.0 1.0 O2B L:GTP1001 2.2 1.0 1.0 CG2 L:THR31 2.3 1.0 1.0 OG1 L:THR31 2.3 1.0 1.0 O3G L:GTP1001 2.4 1.0 1.0 PG L:GTP1001 2.5 1.0 1.0 CB L:THR31 2.8 1.0 1.0 OG1 L:THR48 2.8 1.0 1.0 CG2 L:THR48 2.9 1.0 1.0 PB L:GTP1001 3.1 1.0 1.0 O3B L:GTP1001 3.2 1.0 1.0 CB L:THR48 3.4 1.0 1.0 O3A L:GTP1001 3.5 1.0 1.0 N L:THR31 3.9 1.0 1.0 O2G L:GTP1001 3.9 1.0 1.0 CA L:THR31 3.9 1.0 1.0 O1A L:GTP1001 4.1 1.0 1.0 OD2 L:ASP67 4.2 1.0 1.0 N L:THR48 4.2 1.0 1.0 PA L:GTP1001 4.3 1.0 1.0 O1B L:GTP1001 4.4 1.0 1.0 CG2 L:THR45 4.5 1.0 1.0 CA L:THR48 4.5 1.0 1.0 O L:ILE46 4.5 1.0 1.0 OD1 L:ASN52 4.6 1.0 1.0 CG L:LYS30 4.7 1.0 1.0 NZ L:LYS30 4.7 1.0 1.0 O2A L:GTP1001 4.8 1.0 1.0 CG L:ASP67 4.8 1.0 1.0 OD1 L:ASP67 4.9 1.0 1.0 C L:THR31 5.0 1.0 1.0

Magnesium binding site 6 out of 6 in the Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of Structure of the Cargo Bound Ap-1:ARF1:Tetherin-Nef Stable Closed Trimer within 5.0Å range: probe atom residue distance (Å) B Occ V:Mg1002 b:0.0 occ:1.00 O2G V:GTP1001 1.9 0.6 1.0 O1B V:GTP1001 2.2 0.6 1.0 OG1 V:THR31 2.3 0.8 1.0 O1G V:GTP1001 2.4 0.6 1.0 CG2 V:THR31 2.4 0.8 1.0 PG V:GTP1001 2.5 0.6 1.0 OG1 V:THR48 2.5 0.4 1.0 CB V:THR31 2.9 0.8 1.0 PB V:GTP1001 3.1 0.6 1.0 CG2 V:THR48 3.2 0.4 1.0 O3B V:GTP1001 3.2 0.6 1.0 CB V:THR48 3.4 0.4 1.0 O3A V:GTP1001 3.5 0.6 1.0 N V:THR31 3.8 0.8 1.0 O3G V:GTP1001 3.9 0.6 1.0 N V:THR48 3.9 0.4 1.0 CA V:THR31 4.0 0.8 1.0 O1A V:GTP1001 4.1 0.6 1.0 O V:ILE46 4.1 0.6 1.0 CA V:THR48 4.3 0.4 1.0 PA V:GTP1001 4.3 0.6 1.0 OD2 V:ASP67 4.4 0.1 1.0 CG V:LYS30 4.4 0.0 1.0 CG2 V:THR45 4.4 0.9 1.0 O2B V:GTP1001 4.4 0.6 1.0 O2A V:GTP1001 4.8 0.6 1.0 C V:LYS30 5.0 0.0 1.0 C V:PRO47 5.0 0.5 1.0

K.L.Morris, C.Z.Buffalo, C.M.Sturzel, E.Heusinger, F.Kirchhoff, X.Ren, J.H.Hurley. Hiv-1 Nefs Are Cargo-Sensitive Ap-1 Trimerization Switches in Tetherin Downregulation. Cell V. 174 659 2018.
ISSN: ISSN 1097-4172
PubMed: 30053425
DOI: 10.1016/J.CELL.2018.07.004