Magnesium in PDB 6cvz: Crystal Structure of the WD40-Repeat of RFWD3

All present enzymatic activity of Crystal Structure of the WD40-Repeat of RFWD3:
2.3.2.27;

The structure of Crystal Structure of the WD40-Repeat of RFWD3, PDB code: 6cvz was solved by A.Dong, P.Loppnau, A.Seitova, A.Hutchinson, W.Tempel, Y.Wei, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, Y.Tong, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 1.80
Space group	P 32
Cell size a, b, c (Å), α, β, γ (°)	91.991, 91.991, 110.738, 90.00, 90.00, 120.00
R / Rfree (%)	21.4 / 23.9

The binding sites of Magnesium atom in the Crystal Structure of the WD40-Repeat of RFWD3 (pdb code 6cvz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of the WD40-Repeat of RFWD3, PDB code: 6cvz:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Crystal Structure of the WD40-Repeat of RFWD3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the WD40-Repeat of RFWD3 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg801 b:30.5 occ:1.00 O A:HOH909 2.0 29.5 1.0 O A:HOH991 2.0 32.3 1.0 O A:HOH1020 2.1 32.5 1.0 O A:HOH1016 2.1 29.7 1.0 O A:HOH958 2.1 24.6 1.0 O A:HOH949 2.4 36.5 1.0 OD1 A:ASP748 4.1 29.0 1.0 OE1 A:GLN642 4.1 24.4 1.0 O A:ILE749 4.1 22.9 1.0 O A:HOH1000 4.1 27.8 1.0 O A:MET453 4.3 21.6 1.0 O A:HOH947 4.4 37.0 1.0 O A:HOH1015 4.4 19.9 0.5 O A:HOH1019 4.5 32.7 1.0 O A:HOH999 4.6 28.7 1.0 O A:ASN702 4.6 27.9 1.0 OD2 A:ASP748 4.7 25.6 1.0 NE2 A:GLN642 4.7 24.1 1.0 CD A:GLN642 4.8 22.9 1.0 CG A:ASP748 4.8 25.0 1.0 SG A:CYS750 4.9 28.1 1.0

Magnesium binding site 2 out of 3 in the Crystal Structure of the WD40-Repeat of RFWD3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the WD40-Repeat of RFWD3 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg801 b:41.8 occ:1.00 O B:HOH905 2.0 33.8 1.0 O B:HOH940 2.0 42.6 1.0 O B:HOH945 2.2 31.6 1.0 O B:HOH935 2.3 39.1 1.0 OE1 B:GLN642 4.0 34.9 1.0 O B:ILE749 4.1 28.3 1.0 OD1 B:ASP748 4.1 38.9 1.0 O B:HOH988 4.3 39.6 1.0 O B:MET453 4.4 33.2 1.0 O B:HOH977 4.5 32.2 1.0 O B:ASN702 4.7 37.6 1.0 NE2 B:GLN642 4.7 33.9 1.0 CD B:GLN642 4.7 30.6 1.0 OD2 B:ASP748 4.8 35.0 1.0 CG B:ASP748 4.9 35.7 1.0

Magnesium binding site 3 out of 3 in the Crystal Structure of the WD40-Repeat of RFWD3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of the WD40-Repeat of RFWD3 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg801 b:45.3 occ:1.00 O C:HOH945 2.0 44.6 1.0 O C:HOH968 2.1 38.0 1.0 O C:HOH907 2.1 39.1 1.0 O C:HOH926 2.2 35.6 1.0 O C:HOH906 2.4 44.2 1.0 O C:ILE749 3.8 36.2 1.0 OD1 C:ASP748 4.0 42.4 1.0 O C:HOH969 4.1 33.0 1.0 OE1 C:GLN642 4.1 32.3 1.0 O C:HOH934 4.3 37.8 1.0 O C:MET453 4.4 34.4 1.0 O C:ASN702 4.6 37.2 1.0 SG C:CYS750 4.6 43.2 1.0 O C:HOH954 4.6 40.3 1.0 O C:HOH967 4.7 42.4 1.0 O C:HOH909 4.7 33.7 1.0 CB C:CYS750 4.8 41.9 1.0 C C:ILE749 4.9 40.4 1.0 OD2 C:ASP748 4.9 38.8 1.0 CD C:GLN642 4.9 29.2 1.0 CG C:ASP748 4.9 41.5 1.0 NE2 C:GLN642 4.9 30.8 1.0 CA C:CYS750 4.9 40.3 1.0

P.Loppnau, A.Dong, A.Seitova, A.Hutchinson, W.Tempel, Y.Wei, C.Bountra, C.H.Arrowsmith, A.M.Edwards, P.J.Brown, Y.Tong, Structural Genomics Consortium (Sgc). Crystal Structure of the WD40-Repeat of RFWD3 To Be Published.