Magnesium in PDB 6cwv: Protein Tyrosine Phosphatase 1B A122S Mutant

All present enzymatic activity of Protein Tyrosine Phosphatase 1B A122S Mutant:
3.1.3.48;

The structure of Protein Tyrosine Phosphatase 1B A122S Mutant, PDB code: 6cwv was solved by M.Hjortness, P.Zwart, B.Sankaran, J.M.Fox, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.72 / 1.98
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	89.434, 89.434, 105.554, 90.00, 90.00, 120.00
R / Rfree (%)	20.5 / 24.6

The binding sites of Magnesium atom in the Protein Tyrosine Phosphatase 1B A122S Mutant (pdb code 6cwv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Protein Tyrosine Phosphatase 1B A122S Mutant, PDB code: 6cwv:

Magnesium binding site 1 out of 1 in the Protein Tyrosine Phosphatase 1B A122S Mutant


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Protein Tyrosine Phosphatase 1B A122S Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:51.8 occ:1.00 OE1 A:GLU130 3.5 37.4 1.0 OE1 A:GLU129 3.7 32.8 1.0 OE2 A:GLU130 3.9 45.6 1.0 CD A:GLU130 4.1 35.5 1.0 O A:HOH639 4.3 61.5 1.0 O A:HOH628 4.6 40.5 1.0 CD A:GLU129 4.6 27.7 1.0

M.K.Hjortness, L.Riccardi, A.Hongdusit, P.H.Zwart, B.Sankaran, M.De Vivo, J.M.Fox. Evolutionarily Conserved Allosteric Communication in Protein Tyrosine Phosphatases. Biochemistry V. 57 6443 2018.
ISSN: ISSN 1520-4995
PubMed: 30289703
DOI: 10.1021/ACS.BIOCHEM.8B00656