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Atomistry » Magnesium » PDB 6cu2-6d1v » 6cyb | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 6cu2-6d1v » 6cyb » |
Magnesium in PDB 6cyb: PDE2 in Complex with Compound 7Enzymatic activity of PDE2 in Complex with Compound 7
All present enzymatic activity of PDE2 in Complex with Compound 7:
3.1.4.17; Protein crystallography data
The structure of PDE2 in Complex with Compound 7, PDB code: 6cyb
was solved by
J.Lu,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6cyb:
The structure of PDE2 in Complex with Compound 7 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the PDE2 in Complex with Compound 7
(pdb code 6cyb). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the PDE2 in Complex with Compound 7, PDB code: 6cyb: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6cybGo back to Magnesium Binding Sites List in 6cyb
Magnesium binding site 1 out
of 2 in the PDE2 in Complex with Compound 7
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6cybGo back to Magnesium Binding Sites List in 6cyb
Magnesium binding site 2 out
of 2 in the PDE2 in Complex with Compound 7
Mono view Stereo pair view
Reference:
S.J.Stachel,
R.Berger,
A.B.Nomland,
A.T.Ginnetti,
D.V.Paone,
D.Wang,
V.Puri,
H.Lange,
J.Drott,
J.Lu,
J.Marcus,
M.P.Dwyer,
S.Suon,
J.M.Uslaner,
S.M.Smith.
Structure-Guided Design and Procognitive Assessment of A Potent and Selective Phosphodiesterase 2A Inhibitor. Acs Med Chem Lett V. 9 815 2018.
Page generated: Mon Sep 30 22:48:51 2024
ISSN: ISSN 1948-5875 PubMed: 30128073 DOI: 10.1021/ACSMEDCHEMLETT.8B00214 |
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