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Atomistry » Magnesium » PDB 6d9m-6dlu » 6ddz | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 6d9m-6dlu » 6ddz » |
Magnesium in PDB 6ddz: Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics TargetEnzymatic activity of Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target
All present enzymatic activity of Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target:
3.1.3.5; Protein crystallography data
The structure of Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target, PDB code: 6ddz
was solved by
F.Forouhar,
C.L.Dieck,
G.Tzoneva,
Z.Carpenter,
A.Ambesi-Impiombato,
M.Sanchez-Martin,
R.Kirschner-Schwabe,
S.Lew,
J.Seetharaman,
A.A.Ferrando,
L.Tong,
Northeast Structural Genomics Consortium (Nesg),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target
(pdb code 6ddz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target, PDB code: 6ddz: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6ddzGo back to Magnesium Binding Sites List in 6ddz
Magnesium binding site 1 out
of 2 in the Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6ddzGo back to Magnesium Binding Sites List in 6ddz
Magnesium binding site 2 out
of 2 in the Crystal Structure of the Double Mutant (D52N/R238W) of NT5C2-537X in the Active State, Northeast Structural Genomics Target
Mono view Stereo pair view
Reference:
C.L.Dieck,
G.Tzoneva,
F.Forouhar,
Z.Carpenter,
A.Ambesi-Impiombato,
M.Sanchez-Martin,
R.Kirschner-Schwabe,
S.Lew,
J.Seetharaman,
L.Tong,
A.A.Ferrando.
Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia. Cancer Cell V. 34 136 2018.
Page generated: Mon Sep 30 23:07:10 2024
ISSN: ISSN 1878-3686 PubMed: 29990496 DOI: 10.1016/J.CCELL.2018.06.003 |
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