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Magnesium in PDB 6ehh: Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588Enzymatic activity of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
All present enzymatic activity of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588:
3.6.1.55; 3.6.1.56; Protein crystallography data
The structure of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588, PDB code: 6ehh
was solved by
R.Gustafsson,
M.Narwal,
A.-S.Jemth,
I.Almlof,
U.Warpman Berglund,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6ehh:
The structure of Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
(pdb code 6ehh). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588, PDB code: 6ehh: Magnesium binding site 1 out of 1 in 6ehhGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Mouse MTH1 Mutant L116M with Inhibitor TH588
![]() Mono view ![]() Stereo pair view
Reference:
M.Narwal,
A.S.Jemth,
R.Gustafsson,
I.Almlof,
U.Warpman Berglund,
T.Helleday,
P.Stenmark.
Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity. Biochemistry V. 57 593 2018.
Page generated: Mon Dec 14 22:38:50 2020
ISSN: ISSN 1520-4995 PubMed: 29281266 DOI: 10.1021/ACS.BIOCHEM.7B01163 |
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