Magnesium in PDB 6ehj: Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound

All present enzymatic activity of Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound:
2.3.1.97; 2.7.10.2;

The structure of Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound, PDB code: 6ehj was solved by I.Perez-Dorado, M.Ritzefeld, E.W.Tate, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.08 / 2.10
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	80.250, 177.540, 58.140, 90.00, 90.00, 90.00
R / Rfree (%)	19.3 / 23.7

The binding sites of Magnesium atom in the Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound (pdb code 6ehj). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound, PDB code: 6ehj:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:51.9 occ:1.00 O A:LEU254 2.6 48.8 1.0 N A:LYS257 2.8 51.9 1.0 N A:VAL259 3.0 36.7 1.0 O2A D:MYA2601 3.0 48.7 1.0 O4A D:MYA2601 3.1 52.9 1.0 N A:ARG258 3.2 45.1 1.0 C A:LYS257 3.3 47.9 1.0 CA A:LYS257 3.3 52.1 1.0 CG2 A:VAL259 3.4 39.1 1.0 CB A:VAL259 3.4 38.3 1.0 N A:SER256 3.5 53.1 1.0 CB A:LYS257 3.6 52.8 1.0 C A:LEU254 3.7 41.9 1.0 C A:ARG255 3.7 53.9 1.0 CA A:VAL259 3.8 36.7 1.0 CA A:ARG255 3.9 50.8 1.0 C A:SER256 3.9 57.3 1.0 O A:LYS257 4.0 48.7 1.0 C A:ARG258 4.0 38.2 1.0 O1A D:MYA2601 4.1 52.1 1.0 P1A D:MYA2601 4.1 60.4 1.0 CA A:ARG258 4.1 47.4 1.0 CG1 A:VAL250 4.1 33.0 1.0 CA A:SER256 4.1 56.7 1.0 N A:ARG255 4.2 47.0 1.0 N A:ALA260 4.3 28.8 1.0 O A:ARG255 4.3 59.4 1.0 P2A D:MYA2601 4.3 58.3 1.0 C A:VAL259 4.6 31.9 1.0 O3A D:MYA2601 4.7 54.6 1.0 CB A:LEU254 4.8 41.7 1.0 CG1 A:VAL259 4.8 34.8 1.0 CA A:LEU254 4.8 41.8 1.0 O6A D:MYA2601 4.9 55.0 1.0 CG A:LYS257 4.9 57.4 1.0 CG2 A:VAL250 5.0 27.1 1.0

Magnesium binding site 2 out of 2 in the Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:49.8 occ:1.00 O4A B:COA502 2.5 53.0 1.0 N B:LYS257 2.7 56.6 1.0 O B:LEU254 2.8 52.3 1.0 N B:VAL259 2.8 46.1 1.0 O2A B:COA502 3.0 54.2 1.0 N B:ARG258 3.2 51.6 1.0 CG2 B:VAL259 3.3 47.9 1.0 CB B:VAL259 3.3 44.5 1.0 C B:LYS257 3.4 51.9 1.0 CA B:LYS257 3.4 56.4 1.0 N B:SER256 3.4 55.5 1.0 CA B:VAL259 3.6 43.4 1.0 CB B:LYS257 3.6 54.5 1.0 C B:ARG255 3.8 55.7 1.0 C B:SER256 3.8 56.9 1.0 C B:ARG258 3.8 48.7 1.0 C B:LEU254 3.9 50.3 1.0 CA B:SER256 4.0 57.0 1.0 P2A B:COA502 4.0 55.8 1.0 CA B:ARG258 4.0 54.1 1.0 CA B:ARG255 4.1 51.0 1.0 O B:LYS257 4.1 48.8 1.0 N B:ALA260 4.2 45.3 1.0 P1A B:COA502 4.2 59.9 1.0 CG B:LYS257 4.3 55.0 1.0 CG1 B:VAL250 4.3 42.4 1.0 C B:VAL259 4.4 43.5 1.0 O B:ARG255 4.5 54.3 1.0 N B:ARG255 4.5 48.9 1.0 O3A B:COA502 4.6 50.2 1.0 O5A B:COA502 4.6 54.6 1.0 O1A B:COA502 4.7 59.0 1.0 CG1 B:VAL259 4.8 41.9 1.0 O B:SER256 4.9 59.0 1.0 O6A B:COA502 5.0 50.0 1.0 O B:ARG258 5.0 50.8 1.0

I.Perez-Dorado, M.Ritzefeld, E.W.Tate. Human N-Myristoyltransferase (NMT1) with Myristoyl-Coa and Peptide Bound To Be Published.