Magnesium in PDB 6f3f: Autoinhibited Src Kinase Bound to Adp

All present enzymatic activity of Autoinhibited Src Kinase Bound to Adp:
2.7.10.2;

The structure of Autoinhibited Src Kinase Bound to Adp, PDB code: 6f3f was solved by F.Von Raussendorf, T.A.Leonard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	52.53 / 2.42
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	51.011, 82.974, 105.051, 90.00, 90.00, 90.00
R / Rfree (%)	20.8 / 26.8

The binding sites of Magnesium atom in the Autoinhibited Src Kinase Bound to Adp (pdb code 6f3f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Autoinhibited Src Kinase Bound to Adp, PDB code: 6f3f:

Magnesium binding site 1 out of 1 in the Autoinhibited Src Kinase Bound to Adp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Autoinhibited Src Kinase Bound to Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:51.4 occ:1.00 O3B A:ADP601 2.1 71.1 1.0 OD2 A:ASP404 2.1 51.9 1.0 O2A A:ADP601 2.3 84.9 1.0 OD1 A:ASN391 2.5 34.1 1.0 CG A:ASP404 2.8 46.4 1.0 HZ1 A:LYS295 2.9 62.1 1.0 HB3 A:ASP404 3.2 47.1 1.0 HB2 A:ASP404 3.3 47.1 1.0 CB A:ASP404 3.3 39.2 1.0 PB A:ADP601 3.5 76.3 1.0 HZ3 A:LYS295 3.6 62.1 1.0 CG A:ASN391 3.6 32.6 1.0 PA A:ADP601 3.6 78.0 1.0 O A:HOH769 3.6 43.6 1.0 NZ A:LYS295 3.7 51.7 1.0 HD21 A:ASN391 3.7 41.1 1.0 OD1 A:ASP404 3.7 44.5 1.0 O A:HOH755 3.7 46.9 1.0 O3A A:ADP601 4.0 77.9 1.0 ND2 A:ASN391 4.0 34.2 1.0 HZ2 A:LYS295 4.2 62.1 1.0 O1B A:ADP601 4.3 84.9 1.0 HE2 A:LYS295 4.4 63.7 1.0 HH22 A:ARG388 4.4 38.8 1.0 O1A A:ADP601 4.4 82.3 1.0 HA A:ASN391 4.5 24.4 1.0 HH21 A:ARG388 4.6 38.8 1.0 O A:HOH732 4.6 33.0 1.0 CE A:LYS295 4.6 53.1 1.0 O A:HOH706 4.6 48.6 1.0 O2B A:ADP601 4.6 74.0 1.0 NH2 A:ARG388 4.6 32.3 1.0 O5' A:ADP601 4.8 79.9 1.0 CB A:ASN391 4.8 26.0 1.0 CA A:ASP404 4.8 36.3 1.0 OD2 A:ASP386 4.8 39.0 1.0 HD12 A:LEU407 4.9 73.2 1.0 HD22 A:ASN391 4.9 41.1 1.0 HB3 A:ASN391 4.9 31.2 1.0 HE3 A:LYS295 5.0 63.7 1.0

F.Von Raussendorf, A.De Ruiter, T.A.Leonard. A Switch in Nucleotide Affinity Governs Activation of the Src and Tec Family Kinases. Sci Rep V. 7 17405 2017.
ISSN: ESSN 2045-2322
PubMed: 29234112
DOI: 10.1038/S41598-017-17703-5