|
Magnesium in PDB 6f7b: Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032Enzymatic activity of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
All present enzymatic activity of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032, PDB code: 6f7b
was solved by
S.J.Holton,
G.Siemeister,
A.Mengel,
W.Bone,
J.Schroeder,
S.Zitzmann-Kolbe,
H.Briem,
A.Fernandez-Montalvan,
S.Prechtl,
U.Moenning,
O.Von Ahsen,
J.Johanssen,
A.Cleve,
V.Puetter,
M.Hitchcock,
F.Von Nussbaum,
M.Brands,
D.Mumberg,
K.Ziegelbauer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6f7b:
The structure of Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
(pdb code 6f7b). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032, PDB code: 6f7b: Magnesium binding site 1 out of 1 in 6f7bGo back to Magnesium Binding Sites List in 6f7b
Magnesium binding site 1 out
of 1 in the Crystal Structure of the Human BUB1 Kinase Domain in Complex with Bay 1816032
Mono view Stereo pair view
Reference:
G.Siemeister,
A.Mengel,
A.E.Fernandez-Montalvan,
W.Bone,
J.Schroder,
S.Zitzmann-Kolbe,
H.Briem,
S.Prechtl,
S.J.Holton,
U.Monning,
O.Von Ahsen,
S.Johanssen,
A.Cleve,
V.Putter,
M.Hitchcock,
F.Von Nussbaum,
M.Brands,
K.Ziegelbauer,
D.Mumberg.
Inhibition of BUB1 Kinase By Bay 1816032 Sensitizes Tumor Cells Toward Taxanes, Atr, and Parp Inhibitorsin Vitroandin Vivo. Clin.Cancer Res. V. 25 1404 2019.
Page generated: Mon Dec 14 22:40:19 2020
ISSN: ISSN 1078-0432 PubMed: 30429199 DOI: 10.1158/1078-0432.CCR-18-0628 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |