Magnesium in PDB 6fbv: Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin

Enzymatic activity of Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin

All present enzymatic activity of Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin:
2.7.7.6;

Other elements in 6fbv:

The structure of Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin also contains other interesting chemical elements:

Chlorine	(Cl)	2 atoms
Zinc	(Zn)	2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin (pdb code 6fbv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin, PDB code: 6fbv:

Magnesium binding site 1 out of 1 in 6fbv

Go back to

Magnesium Binding Sites List in 6fbv

Magnesium binding site 1 out of 1 in the Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Single Particle Cryo Em Structure of Mycobacterium Tuberculosis Rna Polymerase in Complex with Fidaxomicin within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
D:Mg1903 b:54.3 occ:1.00	OD2	D:ASP535	2.0	50.5	1.0
	O	D:HOH2002	2.1	36.7	1.0
	OD1	D:ASP539	2.3	43.6	1.0
	OD1	D:ASP535	2.3	53.3	1.0
	OD1	D:ASP537	2.4	43.1	1.0
	CG	D:ASP535	2.5	51.6	1.0
	CG	D:ASP539	3.2	40.9	1.0
	OD2	D:ASP539	3.3	38.2	1.0
	CG	D:ASP537	3.3	41.1	1.0
	OD2	D:ASP537	3.6	48.1	1.0
	CB	D:ASP535	4.0	37.9	1.0
	CB	D:ASP539	4.6	36.3	1.0
	N	D:ASP537	4.6	31.4	1.0
	CB	D:ASP537	4.7	31.8	1.0
	O	D:ASP537	4.7	26.0	1.0
	C	D:ASP537	4.7	25.4	1.0
	CA	D:ASP535	4.8	36.2	1.0
	N	D:ASP539	4.8	29.5	1.0
	N	D:ASP535	4.8	43.6	1.0
	CA	D:ASP537	4.9	26.8	1.0
	C	D:ASP535	4.9	39.2	1.0
	NH2	D:ARG500	4.9	53.9	1.0
	O	D:ASP535	5.0	42.5	1.0

Reference:

W.Lin, K.Das, D.Degen, A.Mazumder, D.Duchi, D.Wang, Y.W.Ebright, R.Y.Ebright, E.Sineva, M.Gigliotti, A.Srivastava, S.Mandal, Y.Jiang, Y.Liu, R.Yin, Z.Zhang, E.T.Eng, D.Thomas, S.Donadio, H.Zhang, C.Zhang, A.N.Kapanidis, R.H.Ebright. Structural Basis of Transcription Inhibition By Fidaxomicin (Lipiarmycin A3). Mol. Cell V. 70 60 2018.
ISSN: ISSN 1097-4164
PubMed: 29606590
DOI: 10.1016/J.MOLCEL.2018.02.026

Page generated: Tue Oct 1 00:19:37 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy