Magnesium in PDB 6fu2: Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp

All present enzymatic activity of Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp:
2.4.2.17;

The structure of Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp, PDB code: 6fu2 was solved by M.S.Alphey, Y.Ge, G.Fisher, C.M.Czekster, J.H.Naismith, R.G.Da Silva, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.05 / 2.71
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	102.720, 146.200, 94.510, 90.00, 102.16, 90.00
R / Rfree (%)	20.1 / 24.3

The binding sites of Magnesium atom in the Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp (pdb code 6fu2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp, PDB code: 6fu2:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg303 b:89.3 occ:1.00 O2A D:PRP301 2.0 0.2 1.0 O2B D:ATP302 2.4 0.6 1.0 O1A D:ATP302 2.5 0.5 1.0 O2B D:PRP301 3.0 0.3 1.0 O3B D:PRP301 3.1 0.2 1.0 O3A D:ATP302 3.3 0.9 1.0 PB D:ATP302 3.4 0.9 1.0 PA D:PRP301 3.4 0.5 1.0 PA D:ATP302 3.5 98.8 1.0 O2G D:ATP302 3.5 0.7 1.0 PB D:PRP301 3.5 0.6 1.0 O3A D:PRP301 3.9 0.9 1.0 O1 D:PRP301 4.0 0.2 1.0 O3B D:ATP302 4.0 0.1 1.0 NH2 C:ARG73 4.2 0.6 1.0 O2A D:ATP302 4.3 99.3 1.0 PG D:ATP302 4.4 0.4 1.0 O1A D:PRP301 4.6 0.2 1.0 NH1 D:ARG32 4.7 0.2 1.0 O5' D:ATP302 4.7 95.5 1.0 O1B D:ATP302 4.7 0.8 1.0 O1B D:PRP301 4.9 0.1 1.0

Magnesium binding site 2 out of 2 in the Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Atp Phosphoribosyltransferase (Hiszg Atpprt) From Psychrobacter Arcticus in Complex with Prpp and Atp within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg304 b:81.5 occ:1.00 O2B C:ATP302 1.9 0.2 1.0 O1A C:PRP301 2.4 82.5 1.0 O2A C:ATP302 2.5 95.7 1.0 O1B C:PRP301 2.5 0.7 1.0 PB C:ATP302 3.3 0.8 1.0 PA C:ATP302 3.5 90.8 1.0 PA C:PRP301 3.6 86.8 1.0 O3A C:PRP301 3.6 91.0 1.0 O3A C:ATP302 3.7 0.1 1.0 PB C:PRP301 3.7 98.1 1.0 O1A C:ATP302 4.2 97.5 1.0 O1B C:ATP302 4.3 0.5 1.0 O3B C:ATP302 4.3 0.2 1.0 O2G C:ATP302 4.3 0.3 1.0 O3G C:ATP302 4.5 0.7 1.0 O2B C:PRP301 4.6 91.6 1.0 NH2 C:ARG32 4.6 95.2 1.0 O1 C:PRP301 4.6 86.0 1.0 O2A C:PRP301 4.6 86.2 1.0 PG C:ATP302 4.7 1.0 1.0 O3B C:PRP301 4.7 95.8 1.0 O5' C:ATP302 4.8 93.3 1.0 NH2 D:ARG73 5.0 0.9 1.0

M.S.Alphey, G.Fisher, J.S.Hirschi, R.Stroek, Y.Ge, E.R.Gould, C.M.Czekster, H.Liu, G.J.Florence, M.J.Vetticatt, J.H.Naismith, R.G.Da Silva. Catalytic and Anticatalytic Snapshots of A Short-Form Atp Phosphoribosyltransferase Acs Catalysis 2018.
ISSN: ESSN 2155-5435
DOI: 10.1021/ACSCATAL.8B00867