Magnesium in PDB 6gp4: Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A

The structure of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A, PDB code: 6gp4 was solved by G.Tassone, C.Pozzi, S.Mangani, M.Botta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.70 / 1.70
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	65.198, 88.936, 100.158, 90.00, 90.00, 90.00
R / Rfree (%)	16.8 / 20.5

The structure of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Magnesium atom in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A (pdb code 6gp4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A, PDB code: 6gp4:

Magnesium binding site 1 out of 1 in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:29.0 occ:0.30 O A:HOH435 2.1 28.8 0.6 O A:HOH663 2.1 32.9 0.6 O A:HOH538 2.1 27.1 0.6 O A:HOH632 3.8 51.5 1.0 O A:HOH655 4.3 44.2 1.0 OD2 A:ASP54 4.4 26.2 1.0 OD1 A:ASP54 4.5 25.8 1.0 O A:HOH612 4.6 49.9 1.0 CG A:ASP54 4.8 25.1 1.0 O A:HOH592 4.9 46.4 1.0

G.Tassone, S.Mangani, M.Botta, C.Pozzi. Probing the Role of ARG97 in Heat Shock Protein 90 N-Terminal Domain From the Parasite Leishmania Braziliensis Through Site-Directed Mutagenesis on the Human Counterpart. Biochim Biophys Acta V.1866 1190 2018PROTEINS Proteom.
ISSN: ISSN 1878-1454
PubMed: 30248409
DOI: 10.1016/J.BBAPAP.2018.09.005