Magnesium in PDB 6gp8: Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp

The structure of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp, PDB code: 6gp8 was solved by G.Tassone, C.Pozzi, S.Mangani, M.Botta, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.70 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.777, 42.034, 54.370, 90.00, 116.39, 90.00
R / Rfree (%)	16.3 / 20

The binding sites of Magnesium atom in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp (pdb code 6gp8). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp, PDB code: 6gp8:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg302 b:15.4 occ:1.00 O1A A:APC301 1.9 13.1 1.0 OD1 A:ASN51 2.0 12.7 1.0 O1B A:APC301 2.0 20.6 1.0 O A:HOH465 2.1 19.0 1.0 O A:HOH530 2.3 19.1 1.0 O2G A:APC301 2.3 25.9 1.0 CG A:ASN51 3.1 12.6 1.0 PA A:APC301 3.2 14.1 1.0 PB A:APC301 3.2 16.5 1.0 PG A:APC301 3.4 29.6 1.0 ND2 A:ASN51 3.5 11.4 1.0 C3A A:APC301 3.6 13.5 1.0 O3B A:APC301 3.7 25.0 1.0 O3G A:APC301 3.9 33.7 1.0 O A:HOH422 3.9 14.7 1.0 O5' A:APC301 3.9 12.4 1.0 O A:HOH506 4.1 25.4 1.0 O A:GLU47 4.3 8.7 1.0 O A:HOH524 4.3 24.8 1.0 CB A:ASN51 4.3 11.4 1.0 OE1 A:GLU47 4.4 14.0 1.0 OG A:SER50 4.4 11.9 0.5 O2A A:APC301 4.5 12.4 1.0 CA A:ASN51 4.5 11.5 1.0 N A:ASN51 4.5 11.4 1.0 O2B A:APC301 4.5 14.1 1.0 OD2 A:ASP54 4.6 17.6 1.0 O1G A:APC301 4.7 28.4 1.0 CB A:SER50 4.9 11.6 0.5 CB A:SER50 4.9 11.9 0.5

Magnesium binding site 2 out of 2 in the Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Human Heat Shock Protein 90-Alpha N-Terminal Domain (HSP90-Ntd) Variant K112A in Complex Ampcpp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg303 b:25.3 occ:1.00 O A:HOH495 2.1 24.3 1.0 OE1 A:GLN6 4.3 28.4 1.0 NE2 A:GLN6 4.7 23.6 1.0 CD A:GLN6 4.9 26.0 1.0

G.Tassone, S.Mangani, M.Botta, C.Pozzi. Probing the Role of ARG97 in Heat Shock Protein 90 N-Terminal Domain From the Parasite Leishmania Braziliensis Through Site-Directed Mutagenesis on the Human Counterpart. Biochim Biophys Acta V.1866 1190 2018PROTEINS Proteom.
ISSN: ISSN 1878-1454
PubMed: 30248409
DOI: 10.1016/J.BBAPAP.2018.09.005