Magnesium in PDB 6hbu: Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium

The binding sites of Magnesium atom in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium (pdb code 6hbu). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium, PDB code: 6hbu:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1502 b:8.3 occ:1.00 OE1 A:GLN211 2.5 9.2 1.0 OG A:SER241 2.9 8.3 1.0 CD A:GLN211 3.2 9.2 1.0 OD1 A:ASP210 3.2 8.9 1.0 CG A:GLN211 3.3 9.2 1.0 OG A:SER87 3.3 8.9 1.0 O1B A:ATP1501 3.5 9.4 1.0 CB A:SER241 3.5 8.3 1.0 O3G A:ATP1501 3.6 9.4 1.0 CB A:LYS86 3.6 8.8 1.0 CE A:LYS86 3.7 8.8 1.0 N A:SER87 4.0 8.9 1.0 O1G A:ATP1501 4.1 9.4 1.0 C A:LYS86 4.3 8.8 1.0 CD A:LYS86 4.3 8.8 1.0 NE2 A:GLN211 4.4 9.2 1.0 PG A:ATP1501 4.4 9.4 1.0 CB A:SER87 4.4 8.9 1.0 CG A:ASP210 4.4 8.9 1.0 PB A:ATP1501 4.4 9.4 1.0 NE2 A:HIS243 4.5 9.7 1.0 CA A:SER87 4.5 8.9 1.0 CA A:LYS86 4.5 8.8 1.0 CG A:LYS86 4.6 8.8 1.0 O2B A:ATP1501 4.6 9.4 1.0 CB A:GLN211 4.6 9.2 1.0 NZ A:LYS86 4.6 8.8 1.0 OE1 A:GLN126 4.8 10.9 1.0 N A:GLN211 4.8 9.2 1.0 O A:LYS86 4.9 8.8 1.0 CA A:SER241 4.9 8.3 1.0 O3B A:ATP1501 5.0 9.4 1.0 OD2 A:ASP210 5.0 8.9 1.0 CD2 A:HIS243 5.0 9.7 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of the ABCG2 E211Q Mutant Bound to Atp and Magnesium within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1502 b:8.4 occ:1.00 OE1 B:GLN211 2.5 9.3 1.0 OG B:SER241 2.9 8.3 1.0 CD B:GLN211 3.2 9.3 1.0 OD1 B:ASP210 3.2 9.2 1.0 CG B:GLN211 3.3 9.3 1.0 OG B:SER87 3.3 9.0 1.0 O1B B:ATP1501 3.5 9.5 1.0 CB B:SER241 3.5 8.3 1.0 O3G B:ATP1501 3.6 9.5 1.0 CB B:LYS86 3.6 9.1 1.0 CE B:LYS86 3.7 9.1 1.0 N B:SER87 4.0 9.0 1.0 O1G B:ATP1501 4.1 9.5 1.0 C B:LYS86 4.3 9.1 1.0 CD B:LYS86 4.3 9.1 1.0 NE2 B:GLN211 4.4 9.3 1.0 PG B:ATP1501 4.4 9.5 1.0 CB B:SER87 4.4 9.0 1.0 CG B:ASP210 4.4 9.2 1.0 PB B:ATP1501 4.4 9.5 1.0 NE2 B:HIS243 4.5 9.7 1.0 CA B:SER87 4.5 9.0 1.0 CA B:LYS86 4.5 9.1 1.0 CG B:LYS86 4.6 9.1 1.0 O2B B:ATP1501 4.6 9.5 1.0 CB B:GLN211 4.6 9.3 1.0 NZ B:LYS86 4.7 9.1 1.0 OE1 B:GLN126 4.8 10.9 1.0 N B:GLN211 4.8 9.3 1.0 O B:LYS86 4.9 9.1 1.0 CA B:SER241 4.9 8.3 1.0 O3B B:ATP1501 5.0 9.5 1.0 OD2 B:ASP210 5.0 9.2 1.0 CD2 B:HIS243 5.0 9.7 1.0

I.Manolaridis, S.M.Jackson, N.M.I.Taylor, J.Kowal, H.Stahlberg, K.P.Locher. Cryo-Em Structures of A Human ABCG2 Mutant Trapped in Atp-Bound and Substrate-Bound States. Nature V. 563 426 2018.
ISSN: ISSN 0028-0836
PubMed: 30405239
DOI: 10.1038/S41586-018-0680-3