Magnesium in PDB 6hea: Pan-Proteasome in State 3

All present enzymatic activity of Pan-Proteasome in State 3:
3.4.25.1;

The binding sites of Magnesium atom in the Pan-Proteasome in State 3 (pdb code 6hea). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the Pan-Proteasome in State 3, PDB code: 6hea:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the Pan-Proteasome in State 3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Pan-Proteasome in State 3 within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg601 b:1.0 occ:1.00 O2G I:ATP401 2.0 1.0 1.0 O2B I:ATP401 2.1 1.0 1.0 O3B I:ATP401 2.3 1.0 1.0 PG I:ATP401 2.8 1.0 1.0 PB I:ATP401 2.8 1.0 1.0 OG1 H:THR189 3.0 1.0 1.0 O1G I:ATP401 3.6 1.0 1.0 OD1 H:ASN288 3.7 1.0 1.0 O1B I:ATP401 3.9 1.0 1.0 O3G I:ATP401 4.0 1.0 1.0 O3A I:ATP401 4.1 1.0 1.0 CB H:THR189 4.1 1.0 1.0 NH2 I:ARG302 4.6 1.0 1.0 N H:THR189 4.7 1.0 1.0 CE H:LYS188 4.8 1.0 1.0 CG H:ASN288 4.9 1.0 1.0 NZ H:LYS188 4.9 1.0 1.0

Magnesium binding site 2 out of 5 in the Pan-Proteasome in State 3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Pan-Proteasome in State 3 within 5.0Å range: probe atom residue distance (Å) B Occ I:Mg403 b:1.0 occ:1.00 O2B I:ATP402 2.3 1.0 1.0 O2G I:ATP402 2.5 1.0 1.0 O3B I:ATP402 2.6 1.0 1.0 OG1 I:THR189 2.7 1.0 1.0 PB I:ATP402 2.9 1.0 1.0 PG I:ATP402 3.1 1.0 1.0 O3A I:ATP402 3.6 1.0 1.0 O3G I:ATP402 4.1 1.0 1.0 CB I:THR189 4.1 1.0 1.0 O1G I:ATP402 4.2 1.0 1.0 O1A I:ATP402 4.2 1.0 1.0 O1B I:ATP402 4.3 1.0 1.0 PA I:ATP402 4.3 1.0 1.0 N I:THR189 4.4 1.0 1.0 O2A I:ATP402 4.5 1.0 1.0 CG I:LYS188 4.6 1.0 1.0 CA I:THR189 4.6 1.0 1.0 CG2 I:THR189 4.9 1.0 1.0 O J:LEU269 5.0 1.0 1.0 OD2 I:ASP241 5.0 1.0 1.0

Magnesium binding site 3 out of 5 in the Pan-Proteasome in State 3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Pan-Proteasome in State 3 within 5.0Å range: probe atom residue distance (Å) B Occ K:Mg402 b:1.0 occ:1.00 O3B K:ADP401 2.9 1.0 1.0 OG1 K:THR189 2.9 1.0 1.0 O3A K:ADP401 3.5 1.0 1.0 PB K:ADP401 3.6 1.0 1.0 OD2 K:ASP241 3.7 1.0 1.0 O2B K:ADP401 3.8 1.0 1.0 OD1 K:ASP241 4.1 1.0 1.0 CB K:THR189 4.1 1.0 1.0 CG K:ASP241 4.2 1.0 1.0 O2A K:ADP401 4.3 1.0 1.0 CA L:ALA270 4.3 1.0 1.0 CB L:ALA270 4.4 1.0 1.0 O L:ALA270 4.5 1.0 1.0 PA K:ADP401 4.6 1.0 1.0 CG2 K:THR189 4.7 1.0 1.0 C L:ALA270 4.9 1.0 1.0

Magnesium binding site 4 out of 5 in the Pan-Proteasome in State 3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Pan-Proteasome in State 3 within 5.0Å range: probe atom residue distance (Å) B Occ M:Mg402 b:1.0 occ:1.00 O2G M:ATP401 2.0 1.0 1.0 O2B M:ATP401 2.2 1.0 1.0 OG1 M:THR189 2.7 1.0 1.0 O3B M:ATP401 3.1 1.0 1.0 PG M:ATP401 3.1 1.0 1.0 PB M:ATP401 3.2 1.0 1.0 CB M:THR189 3.8 1.0 1.0 O1G M:ATP401 3.8 1.0 1.0 N M:THR189 4.0 1.0 1.0 OE2 M:GLU242 4.2 1.0 1.0 CB M:LYS188 4.2 1.0 1.0 O3G M:ATP401 4.3 1.0 1.0 O1B M:ATP401 4.3 1.0 1.0 CE M:LYS188 4.3 1.0 1.0 O M:ASP241 4.4 1.0 1.0 O3A M:ATP401 4.4 1.0 1.0 CA M:THR189 4.4 1.0 1.0 C M:LYS188 4.8 1.0 1.0 CB M:ALA286 4.8 1.0 1.0 NZ M:LYS188 4.9 1.0 1.0

Magnesium binding site 5 out of 5 in the Pan-Proteasome in State 3


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Pan-Proteasome in State 3 within 5.0Å range: probe atom residue distance (Å) B Occ J:Mg402 b:1.0 occ:1.00 O2G J:ATP401 2.3 1.0 1.0 OG1 J:THR189 2.4 1.0 1.0 OD2 J:ASP241 2.4 1.0 1.0 O K:GLY274 2.6 1.0 1.0 O3G J:ATP401 3.1 1.0 1.0 PG J:ATP401 3.1 1.0 1.0 CB J:THR189 3.4 1.0 1.0 CG J:ASP241 3.4 1.0 1.0 CA J:THR189 3.6 1.0 1.0 C K:GLY274 3.7 1.0 1.0 CG2 J:THR189 3.8 1.0 1.0 N J:THR189 4.1 1.0 1.0 O3B J:ATP401 4.1 1.0 1.0 CB J:ASP241 4.1 1.0 1.0 CA K:GLY274 4.3 1.0 1.0 OD1 J:ASP241 4.3 1.0 1.0 O1G J:ATP401 4.4 1.0 1.0 N K:PHE275 4.8 1.0 1.0 C J:LYS188 4.9 1.0 1.0

P.Majumder, T.Rudack, F.Beck, R.Danev, G.Pfeifer, I.Nagy, W.Baumeister. Cryo-Em Structures of the Archaeal Pan-Proteasome Reveal An Around-the-Ring Atpase Cycle. Proc. Natl. Acad. Sci. V. 116 534 2019U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30559193
DOI: 10.1073/PNAS.1817752116