Magnesium in PDB 6hed: Pan-Proteasome in State 5

All present enzymatic activity of Pan-Proteasome in State 5:
3.4.25.1;

The binding sites of Magnesium atom in the Pan-Proteasome in State 5 (pdb code 6hed). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the Pan-Proteasome in State 5, PDB code: 6hed:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5;

Magnesium binding site 1 out of 5 in the Pan-Proteasome in State 5


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Pan-Proteasome in State 5 within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg402 b:1.0 occ:1.00 O2G H:ATP401 2.0 1.0 1.0 O2B H:ATP401 2.1 1.0 1.0 O3B H:ATP401 2.7 1.0 1.0 PG H:ATP401 2.8 1.0 1.0 PB H:ATP401 3.0 1.0 1.0 O1G H:ATP401 3.6 1.0 1.0 OG1 H:THR189 3.6 1.0 1.0 O1B H:ATP401 4.0 1.0 1.0 O3G H:ATP401 4.1 1.0 1.0 NZ H:LYS188 4.3 1.0 1.0 O3A H:ATP401 4.3 1.0 1.0 CE H:LYS188 4.3 1.0 1.0 OE2 H:GLU242 4.4 1.0 1.0 OD1 H:ASN288 4.5 1.0 1.0 NH2 I:ARG302 4.8 1.0 1.0 CD H:GLU242 4.8 1.0 1.0 CB H:THR189 4.8 1.0 1.0 OE1 H:GLU242 4.8 1.0 1.0 NH2 I:ARG299 4.9 1.0 1.0 N H:THR189 4.9 1.0 1.0 CB H:LYS188 4.9 1.0 1.0

Magnesium binding site 2 out of 5 in the Pan-Proteasome in State 5


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Pan-Proteasome in State 5 within 5.0Å range: probe atom residue distance (Å) B Occ I:Mg402 b:1.0 occ:1.00 O3B I:ADP401 2.9 1.0 1.0 OG1 I:THR189 2.9 1.0 1.0 O3A I:ADP401 3.8 1.0 1.0 PB I:ADP401 3.9 1.0 1.0 CB I:THR189 4.2 1.0 1.0 OD2 I:ASP241 4.2 1.0 1.0 O2A I:ADP401 4.2 1.0 1.0 CA J:ALA270 4.2 1.0 1.0 CB J:ALA270 4.3 1.0 1.0 O1B I:ADP401 4.3 1.0 1.0 OD1 I:ASP241 4.3 1.0 1.0 CG2 I:THR189 4.4 1.0 1.0 O J:ALA270 4.5 1.0 1.0 PA I:ADP401 4.6 1.0 1.0 CG I:ASP241 4.6 1.0 1.0 C J:ALA270 4.8 1.0 1.0

Magnesium binding site 3 out of 5 in the Pan-Proteasome in State 5


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Pan-Proteasome in State 5 within 5.0Å range: probe atom residue distance (Å) B Occ K:Mg402 b:1.0 occ:1.00 O2G K:ATP401 2.0 1.0 1.0 O2B K:ATP401 2.1 1.0 1.0 OG1 K:THR189 2.7 1.0 1.0 O3B K:ATP401 2.9 1.0 1.0 PG K:ATP401 3.1 1.0 1.0 PB K:ATP401 3.1 1.0 1.0 NH2 L:ARG302 3.9 1.0 1.0 O1G K:ATP401 4.1 1.0 1.0 O3A K:ATP401 4.1 1.0 1.0 CB K:THR189 4.2 1.0 1.0 O3G K:ATP401 4.2 1.0 1.0 CE K:LYS188 4.3 1.0 1.0 O1B K:ATP401 4.4 1.0 1.0 N K:THR189 4.4 1.0 1.0 OE1 K:GLU242 4.6 1.0 1.0 CB K:LYS188 4.6 1.0 1.0 NZ K:LYS188 4.6 1.0 1.0 CA K:THR189 4.9 1.0 1.0 CG2 K:THR189 5.0 1.0 1.0

Magnesium binding site 4 out of 5 in the Pan-Proteasome in State 5


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Pan-Proteasome in State 5 within 5.0Å range: probe atom residue distance (Å) B Occ L:Mg402 b:1.0 occ:1.00 O2G L:ATP401 2.0 1.0 1.0 O2B L:ATP401 2.2 1.0 1.0 O3B L:ATP401 2.6 1.0 1.0 PG L:ATP401 2.9 1.0 1.0 PB L:ATP401 2.9 1.0 1.0 OG1 L:THR189 3.0 1.0 1.0 O3A L:ATP401 3.8 1.0 1.0 O3G L:ATP401 3.8 1.0 1.0 O1G L:ATP401 4.0 1.0 1.0 NZ L:LYS188 4.2 1.0 1.0 CB L:THR189 4.2 1.0 1.0 O1B L:ATP401 4.3 1.0 1.0 NH2 M:ARG302 4.3 1.0 1.0 OD2 L:ASP241 4.7 1.0 1.0 N L:THR189 4.7 1.0 1.0 OD1 L:ASP241 4.7 1.0 1.0 CE L:LYS188 5.0 1.0 1.0

Magnesium binding site 5 out of 5 in the Pan-Proteasome in State 5


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of Pan-Proteasome in State 5 within 5.0Å range: probe atom residue distance (Å) B Occ M:Mg402 b:1.0 occ:1.00 O2B M:ATP401 2.3 1.0 1.0 O2G M:ATP401 2.4 1.0 1.0 OG1 M:THR189 2.7 1.0 1.0 O3B M:ATP401 3.0 1.0 1.0 PB M:ATP401 3.2 1.0 1.0 PG M:ATP401 3.4 1.0 1.0 O3A M:ATP401 4.0 1.0 1.0 CB M:THR189 4.1 1.0 1.0 N M:THR189 4.4 1.0 1.0 O1G M:ATP401 4.4 1.0 1.0 O2A M:ATP401 4.4 1.0 1.0 O3G M:ATP401 4.4 1.0 1.0 CG M:LYS188 4.5 1.0 1.0 O1B M:ATP401 4.5 1.0 1.0 CA M:THR189 4.6 1.0 1.0 CE M:LYS188 4.7 1.0 1.0 PA M:ATP401 4.7 1.0 1.0 O H:LEU269 4.8 1.0 1.0 OE1 M:GLU242 4.9 1.0 1.0 O1A M:ATP401 4.9 1.0 1.0 CD M:LYS188 4.9 1.0 1.0

P.Majumder, T.Rudack, F.Beck, R.Danev, G.Pfeifer, I.Nagy, W.Baumeister. Cryo-Em Structures of the Archaeal Pan-Proteasome Reveal An Around-the-Ring Atpase Cycle. Proc. Natl. Acad. Sci. V. 116 534 2019U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30559193
DOI: 10.1073/PNAS.1817752116