Magnesium in PDB 6hfm: HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae

The structure of HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae, PDB code: 6hfm was solved by E.M.Huber, M.Groll, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 1.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.000, 79.000, 98.900, 90.00, 90.00, 90.00
R / Rfree (%)	16 / 18.6

The binding sites of Magnesium atom in the HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae (pdb code 6hfm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae, PDB code: 6hfm:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg401 b:18.4 occ:1.00 O A:ASN235 2.7 19.0 1.0 O A:HOH598 2.8 38.4 1.0 O A:LEU343 2.9 18.5 1.0 O A:HOH534 2.9 19.4 1.0 O A:HOH549 2.9 19.3 1.0 OD1 A:ASP349 3.0 23.1 1.0 O A:LYS345 3.1 30.7 1.0 OG1 A:THR237 3.5 19.6 1.0 ND2 A:ASN235 3.7 25.6 1.0 C A:ASN235 3.9 18.2 1.0 CG A:ASP349 4.0 22.9 1.0 C A:LEU343 4.0 18.1 1.0 O A:HOH570 4.0 30.1 1.0 C A:LYS345 4.1 29.4 1.0 CG A:ASN235 4.1 23.0 1.0 N A:THR237 4.2 17.8 1.0 C A:LYS344 4.4 22.6 1.0 O A:LYS344 4.4 24.1 1.0 CB A:THR237 4.4 18.2 1.0 CA A:ASP349 4.5 20.1 1.0 OD1 A:ASN235 4.6 25.4 1.0 N A:LYS345 4.6 23.7 1.0 N A:VAL350 4.6 16.9 1.0 CB A:ASN235 4.6 21.3 1.0 CA A:ILE236 4.7 17.3 1.0 OD2 A:ASP349 4.7 25.3 1.0 O A:VAL350 4.7 17.7 1.0 C A:ILE236 4.8 18.1 1.0 CB A:ASP349 4.8 21.3 1.0 N A:ILE236 4.8 17.3 1.0 CA A:LYS344 4.8 21.3 1.0 N A:LYS344 4.8 18.6 1.0 CA A:GLU346 4.9 35.8 1.0 CA A:LEU343 4.9 17.1 1.0 N A:GLU346 4.9 33.1 1.0 CA A:ASN235 4.9 19.2 1.0 CA A:THR237 5.0 17.1 1.0 C A:ASP349 5.0 18.5 1.0

Magnesium binding site 2 out of 2 in the HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of HSP90 Co-Chaperone CNS1 C-Domain From Saccharomyces Cerevisiae within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg401 b:21.8 occ:1.00 O B:HOH620 2.5 45.0 1.0 O B:ASN235 2.7 20.1 1.0 O B:LEU343 2.9 19.0 1.0 O B:HOH533 2.9 18.5 1.0 O B:HOH542 3.0 21.8 1.0 O B:LYS345 3.1 27.5 1.0 OD1 B:ASP349 3.1 22.9 1.0 OG1 B:THR237 3.7 21.6 1.0 ND2 B:ASN235 3.8 25.4 1.0 O B:HOH551 3.9 37.1 1.0 CG B:ASP349 3.9 22.6 1.0 C B:ASN235 3.9 19.8 1.0 C B:LEU343 4.0 17.6 1.0 C B:LYS345 4.2 27.5 1.0 N B:THR237 4.2 18.7 1.0 CG B:ASN235 4.2 23.3 1.0 C B:LYS344 4.4 21.8 1.0 O B:LYS344 4.4 24.4 1.0 CA B:ASP349 4.5 19.8 1.0 CA B:ILE236 4.6 19.2 1.0 N B:VAL350 4.6 16.6 1.0 OD2 B:ASP349 4.6 25.8 1.0 CB B:THR237 4.6 19.8 1.0 N B:LYS345 4.7 23.1 1.0 CB B:ASN235 4.7 21.8 1.0 CB B:ASP349 4.7 21.2 1.0 O B:VAL350 4.7 17.4 1.0 CA B:LYS344 4.7 20.2 1.0 N B:ILE236 4.7 18.7 1.0 C B:ILE236 4.7 19.3 1.0 OD1 B:ASN235 4.8 25.4 1.0 N B:LYS344 4.8 18.6 1.0 CA B:LEU343 4.9 17.0 1.0 C B:ASP349 5.0 18.8 1.0 CA B:ASN235 5.0 20.2 1.0 N B:GLU346 5.0 29.3 1.0

F.H.Schopf, E.M.Huber, C.Dodt, A.Lopez, M.M.Biebl, D.A.Rutz, M.Muhlhofer, G.Richter, T.Madl, M.Sattler, M.Groll, J.Buchner. The Co-Chaperone CNS1 and the Recruiter Protein HGH1 Link HSP90 to Translation Elongation Via Chaperoning Elongation Factor 2. Mol.Cell V. 74 73 2019.
ISSN: ISSN 1097-2765
PubMed: 30876805
DOI: 10.1016/J.MOLCEL.2019.02.011