Magnesium in PDB 6k7n: Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State)

All present enzymatic activity of Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State):
7.6.2.1;

The structure of Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State) also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Aluminium	(Al)	1 atom

The binding sites of Magnesium atom in the Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State) (pdb code 6k7n). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State), PDB code: 6k7n:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of the Human P4-Type Flippase ATP8A1-CDC50 (E1P State) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1303 b:67.8 occ:1.00 F3 A:ALF1301 2.0 74.1 1.0 OD1 A:ASP409 2.2 70.7 1.0 O A:THR411 2.4 78.8 1.0 OD1 A:ASP786 2.5 64.5 1.0 CG A:ASP786 3.4 64.5 1.0 CG A:ASP409 3.5 70.7 1.0 C A:THR411 3.6 78.8 1.0 AL A:ALF1301 3.6 74.1 1.0 F1 A:ALF1301 3.6 74.1 1.0 OD2 A:ASP790 3.7 62.2 1.0 OD2 A:ASP786 3.7 64.5 1.0 OE1 A:GLU807 3.7 81.1 1.0 OD2 A:ASP409 4.2 70.7 1.0 N A:GLY787 4.2 64.2 1.0 CB A:THR411 4.3 78.8 1.0 CA A:THR411 4.3 78.8 1.0 F2 A:ALF1301 4.4 74.1 1.0 N A:THR411 4.4 78.8 1.0 N A:ASP786 4.5 64.5 1.0 CB A:ASP409 4.5 70.7 1.0 C A:ASP786 4.6 64.5 1.0 CA A:GLY787 4.6 64.2 1.0 N A:GLY412 4.6 76.3 1.0 CG2 A:THR411 4.7 78.8 1.0 CB A:ASP786 4.7 64.5 1.0 CG A:ASP790 4.8 62.2 1.0 CA A:ASP786 4.8 64.5 1.0 OG1 A:THR413 4.8 69.7 1.0 CD A:GLU807 4.9 81.1 1.0 CA A:GLY412 4.9 76.3 1.0

M.Hiraizumi, K.Yamashita, T.Nishizawa, O.Nureki. Cryo-Em Structures Capture the Transport Cycle of the P4-Atpase Flippase. Science V. 365 1149 2019.
ISSN: ESSN 1095-9203
PubMed: 31416931
DOI: 10.1126/SCIENCE.AAY3353