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Magnesium in PDB 6kdz: Crystal Structure of PDE10A in Complex with A Triazolopyrimidine InhibitorEnzymatic activity of Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor
All present enzymatic activity of Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor, PDB code: 6kdz
was solved by
Y.Amano,
K.Honbou,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6kdz:
The structure of Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor
(pdb code 6kdz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor, PDB code: 6kdz: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6kdzGo back to Magnesium Binding Sites List in 6kdz
Magnesium binding site 1 out
of 2 in the Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6kdzGo back to Magnesium Binding Sites List in 6kdz
Magnesium binding site 2 out
of 2 in the Crystal Structure of PDE10A in Complex with A Triazolopyrimidine Inhibitor
Mono view Stereo pair view
Reference:
A.Chino,
S.Honda,
M.Morita,
K.Yonezawa,
W.Hamaguchi,
Y.Amano,
H.Moriguchi,
M.Yamazaki,
M.Aota,
M.Tomishima,
N.Masuda.
Synthesis, Sar Study, and Biological Evaluation of Novel 2,3-Dihydro-1H-Imidazo[1,2-A]Benzimidazole Derivatives As Phosphodiesterase 10A Inhibitors. Bioorg.Med.Chem. V. 27 3692 2019.
Page generated: Mon Dec 14 23:05:39 2020
ISSN: ESSN 1464-3391 PubMed: 31301949 DOI: 10.1016/J.BMC.2019.07.010 |
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