Magnesium in PDB 6klb: Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex)

The binding sites of Magnesium atom in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex) (pdb code 6klb). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex), PDB code: 6klb:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1301 b:6.6 occ:1.00 OP2 G:A17 2.2 79.2 1.0 OD1 A:ASP708 3.2 58.1 1.0 O A:THR716 3.4 55.2 1.0 OD2 A:ASP708 3.6 58.1 1.0 P G:A17 3.7 79.2 1.0 CG A:ASP708 3.8 58.1 1.0 OP2 G:U16 3.9 79.1 1.0 O5' G:U16 4.0 79.1 1.0 OP1 G:U16 4.1 79.1 1.0 P G:U16 4.2 79.1 1.0 C3' G:U16 4.4 79.1 1.0 O5' G:A17 4.4 79.2 1.0 O3' G:U16 4.4 79.1 1.0 CD A:LYS707 4.5 62.1 1.0 C A:THR716 4.6 55.2 1.0 OD1 A:ASN718 4.6 57.9 1.0 OP1 G:A17 4.6 79.2 1.0 CA A:PRO717 4.8 45.4 1.0 C A:PRO717 4.9 45.4 1.0 C5' G:U16 4.9 79.1 1.0

Magnesium binding site 2 out of 4 in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex) within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg1301 b:74.1 occ:1.00 OP2 E:A17 2.2 55.4 1.0 OP2 E:U16 3.5 53.2 1.0 P E:A17 3.7 55.4 1.0 O5' E:U16 3.7 53.2 1.0 O D:THR716 3.8 78.9 1.0 OD1 D:ASP708 4.0 66.0 1.0 P E:U16 4.0 53.2 1.0 C3' E:U16 4.2 53.2 1.0 O3' E:U16 4.4 53.2 1.0 OP1 E:U16 4.4 53.2 1.0 O5' E:A17 4.5 55.4 1.0 OP1 E:A17 4.5 55.4 1.0 OD1 D:ASN718 4.7 72.7 1.0 C5' E:U16 4.7 53.2 1.0 CD D:LYS707 4.7 65.0 1.0 C6 E:U16 4.8 53.2 1.0 C D:THR716 4.9 78.9 1.0

Magnesium binding site 3 out of 4 in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex) within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg1302 b:90.4 occ:1.00 O E:HOH1405 2.0 0.8 1.0 O E:HOH1403 2.0 94.0 1.0 O E:HOH1402 2.0 94.2 1.0 O E:HOH1406 2.0 92.4 1.0 O E:HOH1401 2.0 98.1 1.0 O E:HOH1404 2.1 89.7 1.0 OP2 E:A8 3.8 51.4 1.0 OP2 E:A2 4.2 48.1 1.0 O4 E:U3 4.3 51.6 1.0 N7 E:A8 4.6 51.4 1.0 OP1 E:A2 4.9 48.1 1.0 OP2 E:U7 5.0 55.4 1.0 P E:A2 5.0 48.1 1.0 O2' E:A1 5.0 48.3 1.0

Magnesium binding site 4 out of 4 in the Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of LBCAS12A-Crrna Complex Bound to ACRVA4 (Form B Complex) within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg101 b:0.7 occ:1.00 O G:HOH204 2.0 0.8 1.0 O G:HOH201 2.0 0.3 1.0 O G:HOH202 2.0 0.6 1.0 O G:HOH203 2.0 0.9 1.0 O G:HOH205 2.1 0.4 1.0 OP2 G:A8 3.5 77.4 1.0 OP2 G:U7 3.8 79.4 1.0 O4 G:U3 4.3 76.7 1.0 O5' G:U7 4.4 79.4 1.0 P G:U7 4.5 79.4 1.0 OP2 G:A2 4.7 74.4 1.0 CD B:LYS202 4.8 54.8 1.0 OP1 G:U7 4.8 79.4 1.0 CG B:LYS202 4.8 54.8 1.0

R.Peng, Z.Li, Y.Xu, S.He, Q.Peng, L.A.Wu, Y.Wu, J.Qi, P.Wang, Y.Shi, G.F.Gao. Structural Insight Into Multistage Inhibition of Crispr-CAS12A By ACRVA4. Proc.Natl.Acad.Sci.Usa V. 116 18928 2019.
ISSN: ESSN 1091-6490
PubMed: 31467167
DOI: 10.1073/PNAS.1909400116