Magnesium in PDB 6ltg: Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B

The structure of Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B, PDB code: 6ltg was solved by M.Nishimura, B.D.Novita, T.Kato, L.H.Tjan, B.Wang, A.Wakata, A.L.Poetranto, A.Kawabata, H.Tang, T.Aoshi, Y.Mori, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.65 / 1.63
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	81.380, 95.200, 113.780, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 20.4

The binding sites of Magnesium atom in the Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B (pdb code 6ltg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B, PDB code: 6ltg:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:12.2 occ:0.54 O B:HOH607 2.0 18.2 1.0 O A:HOH703 2.1 20.3 1.0 O B:HOH614 2.1 20.7 1.0 O A:HOH450 2.1 16.9 1.0 O B:HOH415 2.2 16.9 1.0 O A:HOH644 2.2 18.5 1.0 O A:HOH626 4.0 31.6 1.0 O B:HOH351 4.1 15.6 1.0 O B:HOH612 4.2 32.8 1.0 O A:LEU45 4.3 15.6 1.0 O A:HOH548 4.3 24.2 1.0 O A:HOH749 4.3 36.7 1.0 O A:HOH742 4.4 43.6 1.0 O B:HOH395 4.4 26.0 1.0 O B:HOH605 4.4 28.6 1.0 O A:HOH542 4.4 20.5 1.0 O A:HOH705 4.4 23.5 1.0 O B:PHE102 4.5 16.4 1.0 O A:HOH608 5.0 4.7 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Fab Fragment of Murine Monoclonal Antibody Ohv-3 Against Human Herpesvirus 6B within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg301 b:12.4 occ:0.53 O D:HOH723 2.0 24.1 1.0 O C:HOH607 2.0 20.9 1.0 O D:HOH728 2.1 21.7 1.0 O C:HOH551 2.1 20.1 1.0 O D:HOH527 2.1 18.5 1.0 O C:HOH346 2.1 16.6 1.0 O D:HOH441 3.9 18.2 1.0 O C:HOH628 4.1 45.9 1.0 O C:HOH556 4.3 30.7 1.0 O C:LEU45 4.3 15.2 1.0 O D:HOH491 4.3 27.1 1.0 O C:HOH603 4.3 24.1 1.0 O C:HOH443 4.4 25.2 1.0 O D:HOH727 4.4 38.1 1.0 O C:HOH467 4.4 19.0 1.0 O D:HOH718 4.5 31.1 1.0 O D:PHE102 4.5 16.5 1.0 CA D:GLY104 5.0 15.7 1.0

M.Nishimura, B.D.Novita, T.Kato, L.H.Tjan, B.Wang, A.Wakata, A.L.Poetranto, A.Kawabata, H.Tang, T.Aoshi, Y.Mori. Structural Basis For the Interaction of Human Herpesvirus 6B Tetrameric Glycoprotein Complex with the Cellular Receptor, Human CD134 Plos Pathog..
ISSN: ESSN 1553-7374
DOI: 10.1371/JOURNAL.PPAT.1008648