Magnesium in PDB 6m8h: Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1

The structure of Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1, PDB code: 6m8h was solved by R.Mascarenhas, J.Goossens, B.Leverson, S.Kothawala, M.Ballicora, K.Olsen, D.De Freitas, D.Liu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.86 / 2.07
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	79.558, 79.558, 105.421, 90.00, 90.00, 120.00
R / Rfree (%)	16.5 / 19.7

The binding sites of Magnesium atom in the Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1 (pdb code 6m8h). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1, PDB code: 6m8h:

Magnesium binding site 1 out of 1 in the Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the R208Q Mutant of G(I) Subunit Alpha-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:27.2 occ:1.00 O A:HOH514 2.0 21.2 1.0 OG A:SER47 2.1 12.8 0.7 O3G A:GSP401 2.1 30.3 1.0 O2B A:GSP401 2.1 12.8 1.0 OG1 A:THR181 2.1 25.1 1.0 O A:HOH528 2.3 20.9 1.0 CB A:SER47 3.0 20.0 0.7 CB A:SER47 3.0 19.9 0.3 CB A:THR181 3.1 23.8 1.0 PB A:GSP401 3.4 14.9 1.0 PG A:GSP401 3.4 32.2 1.0 OD2 A:ASP200 3.6 23.8 1.0 OG A:SER47 3.6 21.0 0.3 O3B A:GSP401 3.7 20.9 1.0 N A:SER47 3.7 17.4 1.0 CA A:SER47 3.9 17.3 0.3 CA A:SER47 3.9 17.2 0.7 CG2 A:THR181 4.0 22.6 1.0 O2G A:GSP401 4.1 25.7 1.0 OD1 A:ASP200 4.1 23.4 1.0 N A:THR181 4.2 20.7 1.0 O1B A:GSP401 4.2 17.1 1.0 CA A:THR181 4.2 24.1 1.0 CG A:ASP200 4.3 17.9 1.0 O2A A:GSP401 4.3 20.3 1.0 O A:HOH597 4.4 44.9 1.0 O3A A:GSP401 4.5 16.7 1.0 O A:HOH668 4.5 37.2 1.0 O A:VAL201 4.6 29.2 1.0 O A:VAL179 4.6 18.9 1.0 CB A:LYS46 4.7 14.6 1.0 PA A:GSP401 4.7 15.1 1.0 CE A:LYS46 4.8 17.1 1.0 C A:LYS46 4.8 20.3 1.0 O1A A:GSP401 4.8 16.9 1.0 S1G A:GSP401 4.9 34.6 1.0

J.L.Goossens, B.D.Leverson, S.Kothawala, R.Mascarenhas, D.Liu, M.Ballicora, K.W.Olsen, D.M.De Freitas. Functional Consequences of Oncogenic Mutations in the Switch II Region of GALPHAI1 and Galphas Proteins To Be Published.