Magnesium in PDB 6mnx: Structural Basis of Impaired Hydrolysis in Kras Mutant
Protein crystallography data
The structure of Structural Basis of Impaired Hydrolysis in Kras Mutant, PDB code: 6mnx
was solved by
A.K.Bera,
K.D.Westover,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
|
Resolution Low / High (Å)
|
47.91 /
2.20
|
|
Space group
|
P 21 21 21
|
|
Cell size a, b, c (Å), α, β, γ (°)
|
56.770,
127.666,
145.031,
90.00,
90.00,
90.00
|
|
R / Rfree (%)
|
20.4 /
25.4
|
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structural Basis of Impaired Hydrolysis in Kras Mutant
(pdb code 6mnx). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 6 binding sites of Magnesium where determined in the
Structural Basis of Impaired Hydrolysis in Kras Mutant, PDB code: 6mnx:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
Magnesium binding site 1 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 1 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg202
b:19.6
occ:1.00
|
HOB2
|
A:GTP201
|
1.7
|
19.4
|
1.0
|
|
HOG2
|
A:GTP201
|
1.7
|
19.4
|
1.0
|
|
OG
|
A:SER17
|
2.0
|
19.1
|
1.0
|
|
O2B
|
A:GTP201
|
2.0
|
16.1
|
1.0
|
|
O2G
|
A:GTP201
|
2.0
|
19.3
|
1.0
|
|
O
|
A:HOH319
|
2.1
|
16.8
|
1.0
|
|
OG1
|
A:THR35
|
2.1
|
17.4
|
1.0
|
|
O
|
A:HOH309
|
2.2
|
17.8
|
1.0
|
|
HB
|
A:THR35
|
3.0
|
26.5
|
1.0
|
|
CB
|
A:SER17
|
3.1
|
18.7
|
1.0
|
|
CB
|
A:THR35
|
3.1
|
22.0
|
1.0
|
|
HB2
|
A:SER17
|
3.1
|
22.5
|
1.0
|
|
H
|
A:SER17
|
3.2
|
22.8
|
1.0
|
|
PB
|
A:GTP201
|
3.2
|
16.2
|
1.0
|
|
PG
|
A:GTP201
|
3.3
|
17.3
|
1.0
|
|
O3B
|
A:GTP201
|
3.4
|
17.0
|
1.0
|
|
H
|
A:THR35
|
3.4
|
23.2
|
1.0
|
|
HB3
|
A:SER17
|
3.8
|
22.5
|
1.0
|
|
OD2
|
A:ASP57
|
3.8
|
23.7
|
1.0
|
|
N
|
A:SER17
|
3.9
|
18.9
|
1.0
|
|
N
|
A:THR35
|
3.9
|
19.2
|
1.0
|
|
HB2
|
A:LYS16
|
4.0
|
23.2
|
1.0
|
|
O3G
|
A:GTP201
|
4.0
|
19.6
|
1.0
|
|
O
|
A:HOH307
|
4.0
|
25.3
|
1.0
|
|
CA
|
A:SER17
|
4.1
|
17.3
|
1.0
|
|
HG21
|
A:THR35
|
4.1
|
25.4
|
1.0
|
|
OD1
|
A:ASP57
|
4.1
|
23.1
|
1.0
|
|
O2A
|
A:GTP201
|
4.1
|
19.1
|
1.0
|
|
HOA2
|
A:GTP201
|
4.1
|
23.0
|
1.0
|
|
CA
|
A:THR35
|
4.1
|
21.8
|
1.0
|
|
O3A
|
A:GTP201
|
4.2
|
18.0
|
1.0
|
|
CG2
|
A:THR35
|
4.2
|
21.1
|
1.0
|
|
HE2
|
A:LYS16
|
4.3
|
25.4
|
1.0
|
|
O1G
|
A:GTP201
|
4.3
|
17.0
|
1.0
|
|
HA
|
A:PRO34
|
4.3
|
27.9
|
1.0
|
|
CG
|
A:ASP57
|
4.3
|
23.0
|
1.0
|
|
O1B
|
A:GTP201
|
4.3
|
16.6
|
1.0
|
|
O
|
A:ASP33
|
4.4
|
19.3
|
1.0
|
|
HA
|
A:SER17
|
4.4
|
20.8
|
1.0
|
|
O
|
A:THR58
|
4.4
|
25.6
|
1.0
|
|
HE1
|
A:TYR32
|
4.5
|
21.9
|
1.0
|
|
PA
|
A:GTP201
|
4.5
|
18.3
|
1.0
|
|
HA
|
A:THR35
|
4.6
|
26.2
|
1.0
|
|
O1A
|
A:GTP201
|
4.7
|
20.9
|
1.0
|
|
HG23
|
A:THR35
|
4.7
|
25.4
|
1.0
|
|
HZ2
|
A:LYS16
|
4.7
|
24.5
|
1.0
|
|
C
|
A:PRO34
|
4.8
|
20.3
|
1.0
|
|
HZ1
|
A:LYS16
|
4.8
|
24.5
|
1.0
|
|
CB
|
A:LYS16
|
4.9
|
19.2
|
1.0
|
|
HG22
|
A:THR35
|
4.9
|
25.4
|
1.0
|
|
HOG3
|
A:GTP201
|
5.0
|
23.7
|
1.0
|
|
HA
|
A:ALA59
|
5.0
|
34.2
|
1.0
|
|
C
|
A:LYS16
|
5.0
|
19.3
|
1.0
|
|
Magnesium binding site 2 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 2 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg202
b:27.4
occ:1.00
|
HOG2
|
B:GTP201
|
1.6
|
28.2
|
1.0
|
|
HOB2
|
B:GTP201
|
1.6
|
28.6
|
1.0
|
|
O2B
|
B:GTP201
|
1.9
|
23.8
|
1.0
|
|
O
|
B:HOH307
|
2.0
|
27.2
|
1.0
|
|
O2G
|
B:GTP201
|
2.0
|
26.9
|
1.0
|
|
O
|
B:HOH317
|
2.1
|
25.7
|
1.0
|
|
OG
|
B:SER17
|
2.2
|
26.6
|
1.0
|
|
OG1
|
B:THR35
|
2.2
|
30.7
|
1.0
|
|
HB
|
B:THR35
|
3.0
|
39.2
|
1.0
|
|
HB2
|
B:SER17
|
3.0
|
27.4
|
1.0
|
|
H
|
B:SER17
|
3.1
|
29.3
|
1.0
|
|
CB
|
B:SER17
|
3.2
|
22.7
|
1.0
|
|
CB
|
B:THR35
|
3.2
|
32.6
|
1.0
|
|
PB
|
B:GTP201
|
3.2
|
22.7
|
1.0
|
|
PG
|
B:GTP201
|
3.2
|
25.8
|
1.0
|
|
O3B
|
B:GTP201
|
3.3
|
28.4
|
1.0
|
|
H
|
B:THR35
|
3.5
|
36.6
|
1.0
|
|
N
|
B:SER17
|
3.8
|
24.4
|
1.0
|
|
O3G
|
B:GTP201
|
3.8
|
26.2
|
1.0
|
|
HB2
|
B:LYS16
|
3.9
|
27.6
|
1.0
|
|
HB3
|
B:SER17
|
3.9
|
27.4
|
1.0
|
|
OD2
|
B:ASP57
|
3.9
|
30.6
|
1.0
|
|
N
|
B:THR35
|
4.0
|
30.4
|
1.0
|
|
HG21
|
B:THR35
|
4.0
|
40.2
|
1.0
|
|
HOA2
|
B:GTP201
|
4.0
|
26.0
|
1.0
|
|
CA
|
B:SER17
|
4.0
|
22.9
|
1.0
|
|
O3A
|
B:GTP201
|
4.1
|
23.5
|
1.0
|
|
O2A
|
B:GTP201
|
4.2
|
21.6
|
1.0
|
|
CA
|
B:THR35
|
4.2
|
33.0
|
1.0
|
|
CG2
|
B:THR35
|
4.2
|
33.4
|
1.0
|
|
O
|
B:HOH305
|
4.2
|
33.1
|
1.0
|
|
O1B
|
B:GTP201
|
4.3
|
20.0
|
1.0
|
|
OD1
|
B:ASP57
|
4.3
|
28.5
|
1.0
|
|
HE2
|
B:LYS16
|
4.3
|
30.7
|
1.0
|
|
HZ1
|
B:LYS16
|
4.4
|
28.7
|
1.0
|
|
HA
|
B:SER17
|
4.4
|
27.5
|
1.0
|
|
O1G
|
B:GTP201
|
4.4
|
26.6
|
1.0
|
|
HA
|
B:PRO34
|
4.4
|
38.4
|
1.0
|
|
PA
|
B:GTP201
|
4.4
|
22.8
|
1.0
|
|
O
|
B:ASP33
|
4.4
|
31.1
|
1.0
|
|
CG
|
B:ASP57
|
4.5
|
29.2
|
1.0
|
|
O1A
|
B:GTP201
|
4.5
|
19.4
|
1.0
|
|
HE1
|
B:TYR32
|
4.5
|
31.2
|
1.0
|
|
O
|
B:THR58
|
4.5
|
32.5
|
1.0
|
|
HA
|
B:THR35
|
4.7
|
39.7
|
1.0
|
|
HZ2
|
B:LYS16
|
4.7
|
28.7
|
1.0
|
|
HG23
|
B:THR35
|
4.8
|
40.2
|
1.0
|
|
CB
|
B:LYS16
|
4.8
|
22.9
|
1.0
|
|
HA
|
B:ALA59
|
4.8
|
44.4
|
1.0
|
|
HOG3
|
B:GTP201
|
4.8
|
31.6
|
1.0
|
|
NZ
|
B:LYS16
|
4.8
|
23.8
|
1.0
|
|
HG22
|
B:THR35
|
4.9
|
40.2
|
1.0
|
|
C
|
B:LYS16
|
4.9
|
24.3
|
1.0
|
|
H
|
B:LYS16
|
4.9
|
29.6
|
1.0
|
|
C
|
B:PRO34
|
4.9
|
30.8
|
1.0
|
|
Magnesium binding site 3 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 3 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg202
b:21.4
occ:1.00
|
HOG2
|
C:GTP201
|
1.6
|
23.8
|
1.0
|
|
HOB2
|
C:GTP201
|
1.7
|
23.7
|
1.0
|
|
OG
|
C:SER17
|
2.0
|
20.4
|
1.0
|
|
O2G
|
C:GTP201
|
2.0
|
23.5
|
1.0
|
|
OG1
|
C:THR35
|
2.0
|
23.9
|
1.0
|
|
O2B
|
C:GTP201
|
2.0
|
19.7
|
1.0
|
|
O
|
C:HOH317
|
2.1
|
23.3
|
1.0
|
|
O
|
C:HOH306
|
2.1
|
25.1
|
1.0
|
|
HB
|
C:THR35
|
2.8
|
29.9
|
1.0
|
|
H
|
C:THR35
|
2.9
|
28.4
|
1.0
|
|
CB
|
C:THR35
|
3.0
|
24.8
|
1.0
|
|
CB
|
C:SER17
|
3.2
|
22.2
|
1.0
|
|
HB2
|
C:SER17
|
3.2
|
26.8
|
1.0
|
|
H
|
C:SER17
|
3.2
|
24.5
|
1.0
|
|
PG
|
C:GTP201
|
3.3
|
26.1
|
1.0
|
|
PB
|
C:GTP201
|
3.3
|
20.5
|
1.0
|
|
O3B
|
C:GTP201
|
3.4
|
22.1
|
1.0
|
|
N
|
C:THR35
|
3.6
|
23.6
|
1.0
|
|
HB3
|
C:SER17
|
3.8
|
26.8
|
1.0
|
|
N
|
C:SER17
|
3.9
|
20.3
|
1.0
|
|
OD2
|
C:ASP57
|
3.9
|
28.8
|
1.0
|
|
CA
|
C:THR35
|
3.9
|
23.1
|
1.0
|
|
O3G
|
C:GTP201
|
4.0
|
26.7
|
1.0
|
|
HB2
|
C:LYS16
|
4.0
|
26.6
|
1.0
|
|
HG21
|
C:THR35
|
4.1
|
28.9
|
1.0
|
|
CA
|
C:SER17
|
4.1
|
21.4
|
1.0
|
|
HOA2
|
C:GTP201
|
4.2
|
20.7
|
1.0
|
|
CG2
|
C:THR35
|
4.2
|
24.0
|
1.0
|
|
O2A
|
C:GTP201
|
4.2
|
17.2
|
1.0
|
|
HE2
|
C:LYS16
|
4.2
|
31.0
|
1.0
|
|
HA
|
C:PRO34
|
4.2
|
27.0
|
1.0
|
|
OD1
|
C:ASP57
|
4.2
|
27.8
|
1.0
|
|
O3A
|
C:GTP201
|
4.3
|
22.1
|
1.0
|
|
O
|
C:HOH312
|
4.3
|
30.0
|
1.0
|
|
O
|
C:ASP33
|
4.3
|
23.1
|
1.0
|
|
HA
|
C:THR35
|
4.4
|
27.8
|
1.0
|
|
O1B
|
C:GTP201
|
4.4
|
22.8
|
1.0
|
|
O1G
|
C:GTP201
|
4.4
|
28.0
|
1.0
|
|
HA
|
C:SER17
|
4.5
|
25.8
|
1.0
|
|
CG
|
C:ASP57
|
4.5
|
26.7
|
1.0
|
|
O1A
|
C:GTP201
|
4.5
|
18.1
|
1.0
|
|
PA
|
C:GTP201
|
4.5
|
20.3
|
1.0
|
|
O
|
C:THR58
|
4.6
|
23.4
|
1.0
|
|
HE1
|
C:TYR32
|
4.6
|
26.4
|
1.0
|
|
C
|
C:PRO34
|
4.7
|
22.6
|
1.0
|
|
HG23
|
C:THR35
|
4.8
|
28.9
|
1.0
|
|
HZ2
|
C:LYS16
|
4.8
|
27.1
|
1.0
|
|
HZ3
|
C:LYS16
|
4.8
|
27.1
|
1.0
|
|
O
|
C:HOH333
|
4.8
|
29.6
|
1.0
|
|
HG22
|
C:THR35
|
4.8
|
28.9
|
1.0
|
|
CA
|
C:PRO34
|
4.9
|
22.4
|
1.0
|
|
CB
|
C:LYS16
|
4.9
|
22.1
|
1.0
|
|
HOG3
|
C:GTP201
|
5.0
|
32.1
|
1.0
|
|
Magnesium binding site 4 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 4 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg202
b:23.9
occ:1.00
|
HOG2
|
D:GTP201
|
1.5
|
26.6
|
1.0
|
|
O2G
|
D:GTP201
|
1.9
|
27.4
|
1.0
|
|
HOB2
|
D:GTP201
|
1.9
|
27.5
|
1.0
|
|
O
|
D:HOH312
|
2.1
|
24.8
|
1.0
|
|
OG1
|
D:THR35
|
2.1
|
25.0
|
1.0
|
|
O2B
|
D:GTP201
|
2.1
|
22.8
|
1.0
|
|
OG
|
D:SER17
|
2.1
|
22.1
|
1.0
|
|
O
|
D:HOH307
|
2.2
|
23.9
|
1.0
|
|
HB
|
D:THR35
|
2.8
|
35.7
|
1.0
|
|
CB
|
D:THR35
|
3.0
|
29.7
|
1.0
|
|
PG
|
D:GTP201
|
3.2
|
27.1
|
1.0
|
|
HB2
|
D:SER17
|
3.2
|
27.2
|
1.0
|
|
H
|
D:THR35
|
3.2
|
34.4
|
1.0
|
|
CB
|
D:SER17
|
3.2
|
22.6
|
1.0
|
|
H
|
D:SER17
|
3.3
|
24.4
|
1.0
|
|
PB
|
D:GTP201
|
3.3
|
21.9
|
1.0
|
|
O3B
|
D:GTP201
|
3.4
|
23.9
|
1.0
|
|
HOA2
|
D:GTP201
|
3.6
|
24.3
|
1.0
|
|
N
|
D:THR35
|
3.7
|
28.6
|
1.0
|
|
HB3
|
D:SER17
|
3.8
|
27.2
|
1.0
|
|
N
|
D:SER17
|
3.9
|
20.3
|
1.0
|
|
CA
|
D:THR35
|
3.9
|
32.2
|
1.0
|
|
O3G
|
D:GTP201
|
4.0
|
26.5
|
1.0
|
|
O2A
|
D:GTP201
|
4.0
|
20.2
|
1.0
|
|
O
|
D:HOH302
|
4.0
|
33.3
|
1.0
|
|
HG21
|
D:THR35
|
4.0
|
36.3
|
1.0
|
|
HB2
|
D:LYS16
|
4.1
|
25.2
|
1.0
|
|
O3A
|
D:GTP201
|
4.1
|
23.6
|
1.0
|
|
CA
|
D:SER17
|
4.1
|
20.8
|
1.0
|
|
OD2
|
D:ASP57
|
4.1
|
29.4
|
1.0
|
|
CG2
|
D:THR35
|
4.2
|
30.2
|
1.0
|
|
O1G
|
D:GTP201
|
4.2
|
28.7
|
1.0
|
|
OD1
|
D:ASP57
|
4.3
|
27.9
|
1.0
|
|
HA
|
D:THR35
|
4.3
|
38.7
|
1.0
|
|
O
|
D:ASP33
|
4.3
|
25.9
|
1.0
|
|
HA
|
D:PRO34
|
4.3
|
32.1
|
1.0
|
|
HE2
|
D:LYS16
|
4.4
|
31.4
|
1.0
|
|
PA
|
D:GTP201
|
4.4
|
19.8
|
1.0
|
|
HZ1
|
D:LYS16
|
4.4
|
32.2
|
1.0
|
|
HE1
|
D:TYR32
|
4.5
|
28.0
|
1.0
|
|
O1A
|
D:GTP201
|
4.5
|
21.1
|
1.0
|
|
O1B
|
D:GTP201
|
4.5
|
20.7
|
1.0
|
|
HA
|
D:SER17
|
4.5
|
25.0
|
1.0
|
|
O
|
D:THR58
|
4.6
|
29.5
|
1.0
|
|
CG
|
D:ASP57
|
4.6
|
28.3
|
1.0
|
|
C
|
D:PRO34
|
4.7
|
26.5
|
1.0
|
|
HG23
|
D:THR35
|
4.7
|
36.3
|
1.0
|
|
HG22
|
D:THR35
|
4.8
|
36.3
|
1.0
|
|
O
|
D:HOH333
|
4.9
|
29.4
|
1.0
|
|
HOG3
|
D:GTP201
|
5.0
|
31.9
|
1.0
|
|
CB
|
D:LYS16
|
5.0
|
20.9
|
1.0
|
|
CA
|
D:PRO34
|
5.0
|
26.6
|
1.0
|
|
Magnesium binding site 5 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 5 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Mg202
b:20.7
occ:1.00
|
HOB2
|
E:GTP201
|
1.7
|
21.9
|
1.0
|
|
HOG2
|
E:GTP201
|
1.7
|
20.6
|
1.0
|
|
OG1
|
E:THR35
|
1.9
|
18.4
|
1.0
|
|
OG
|
E:SER17
|
2.0
|
19.8
|
1.0
|
|
O2B
|
E:GTP201
|
2.0
|
18.1
|
1.0
|
|
O
|
E:HOH317
|
2.1
|
19.9
|
1.0
|
|
O2G
|
E:GTP201
|
2.1
|
22.0
|
1.0
|
|
O
|
E:HOH302
|
2.2
|
18.2
|
1.0
|
|
HB
|
E:THR35
|
2.9
|
25.0
|
1.0
|
|
HB2
|
E:SER17
|
3.0
|
25.1
|
1.0
|
|
CB
|
E:THR35
|
3.0
|
20.7
|
1.0
|
|
CB
|
E:SER17
|
3.1
|
20.9
|
1.0
|
|
H
|
E:THR35
|
3.3
|
28.6
|
1.0
|
|
H
|
E:SER17
|
3.4
|
23.8
|
1.0
|
|
PB
|
E:GTP201
|
3.4
|
20.2
|
1.0
|
|
PG
|
E:GTP201
|
3.4
|
21.7
|
1.0
|
|
O3B
|
E:GTP201
|
3.6
|
19.7
|
1.0
|
|
HB3
|
E:SER17
|
3.7
|
25.1
|
1.0
|
|
N
|
E:THR35
|
3.8
|
23.8
|
1.0
|
|
N
|
E:SER17
|
3.9
|
19.8
|
1.0
|
|
OD2
|
E:ASP57
|
3.9
|
26.8
|
1.0
|
|
HG21
|
E:THR35
|
3.9
|
24.5
|
1.0
|
|
HB2
|
E:LYS16
|
4.0
|
22.0
|
1.0
|
|
CA
|
E:THR35
|
4.0
|
24.7
|
1.0
|
|
CA
|
E:SER17
|
4.0
|
19.3
|
1.0
|
|
O
|
E:HOH322
|
4.1
|
27.1
|
1.0
|
|
CG2
|
E:THR35
|
4.1
|
20.4
|
1.0
|
|
O3G
|
E:GTP201
|
4.1
|
21.9
|
1.0
|
|
OD1
|
E:ASP57
|
4.1
|
24.7
|
1.0
|
|
HOA2
|
E:GTP201
|
4.2
|
24.9
|
1.0
|
|
O2A
|
E:GTP201
|
4.2
|
20.6
|
1.0
|
|
O3A
|
E:GTP201
|
4.2
|
20.7
|
1.0
|
|
HE2
|
E:LYS16
|
4.2
|
25.4
|
1.0
|
|
HA
|
E:SER17
|
4.3
|
23.2
|
1.0
|
|
HA
|
E:PRO34
|
4.4
|
30.0
|
1.0
|
|
O
|
E:THR58
|
4.4
|
21.3
|
1.0
|
|
CG
|
E:ASP57
|
4.4
|
24.0
|
1.0
|
|
O1B
|
E:GTP201
|
4.4
|
19.3
|
1.0
|
|
O
|
E:ASP33
|
4.4
|
26.8
|
1.0
|
|
HA
|
E:THR35
|
4.5
|
29.7
|
1.0
|
|
O1G
|
E:GTP201
|
4.5
|
24.4
|
1.0
|
|
HG23
|
E:THR35
|
4.5
|
24.5
|
1.0
|
|
PA
|
E:GTP201
|
4.6
|
21.1
|
1.0
|
|
HE1
|
E:TYR32
|
4.7
|
27.5
|
1.0
|
|
O1A
|
E:GTP201
|
4.7
|
19.2
|
1.0
|
|
HZ1
|
E:LYS16
|
4.7
|
26.4
|
1.0
|
|
C
|
E:PRO34
|
4.7
|
24.2
|
1.0
|
|
HG22
|
E:THR35
|
4.8
|
24.5
|
1.0
|
|
CB
|
E:LYS16
|
4.9
|
18.3
|
1.0
|
|
C
|
E:LYS16
|
4.9
|
20.5
|
1.0
|
|
Magnesium binding site 6 out
of 6 in 6mnx
Go back to
Magnesium Binding Sites List in 6mnx
Magnesium binding site 6 out
of 6 in the Structural Basis of Impaired Hydrolysis in Kras Mutant
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Structural Basis of Impaired Hydrolysis in Kras Mutant within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg202
b:30.1
occ:1.00
|
HOG2
|
F:GTP201
|
1.6
|
33.0
|
1.0
|
|
HOB2
|
F:GTP201
|
1.6
|
37.6
|
1.0
|
|
OG1
|
F:THR35
|
1.9
|
32.9
|
1.0
|
|
OG
|
F:SER17
|
2.0
|
25.3
|
1.0
|
|
O2B
|
F:GTP201
|
2.0
|
31.3
|
1.0
|
|
O
|
F:HOH302
|
2.1
|
34.7
|
1.0
|
|
O2G
|
F:GTP201
|
2.2
|
34.9
|
1.0
|
|
O
|
F:HOH301
|
2.3
|
28.7
|
1.0
|
|
HB2
|
F:SER17
|
2.8
|
35.7
|
1.0
|
|
HB
|
F:THR35
|
2.9
|
39.8
|
1.0
|
|
CB
|
F:SER17
|
3.0
|
29.7
|
1.0
|
|
CB
|
F:THR35
|
3.0
|
33.1
|
1.0
|
|
H
|
F:SER17
|
3.1
|
44.8
|
1.0
|
|
H
|
F:THR35
|
3.3
|
38.8
|
1.0
|
|
PB
|
F:GTP201
|
3.4
|
29.8
|
1.0
|
|
PG
|
F:GTP201
|
3.4
|
30.6
|
1.0
|
|
O3B
|
F:GTP201
|
3.5
|
26.6
|
1.0
|
|
HOA2
|
F:GTP201
|
3.6
|
34.6
|
1.0
|
|
HB3
|
F:SER17
|
3.7
|
35.7
|
1.0
|
|
N
|
F:SER17
|
3.7
|
37.2
|
1.0
|
|
OD2
|
F:ASP57
|
3.8
|
38.8
|
1.0
|
|
N
|
F:THR35
|
3.8
|
32.2
|
1.0
|
|
HG21
|
F:THR35
|
3.9
|
41.7
|
1.0
|
|
CA
|
F:SER17
|
3.9
|
34.1
|
1.0
|
|
HB2
|
F:LYS16
|
3.9
|
39.8
|
1.0
|
|
CA
|
F:THR35
|
4.0
|
30.4
|
1.0
|
|
O2A
|
F:GTP201
|
4.0
|
28.8
|
1.0
|
|
O3G
|
F:GTP201
|
4.0
|
34.9
|
1.0
|
|
CG2
|
F:THR35
|
4.0
|
34.7
|
1.0
|
|
OD1
|
F:ASP57
|
4.1
|
39.8
|
1.0
|
|
O
|
F:HOH304
|
4.2
|
35.5
|
1.0
|
|
HA
|
F:SER17
|
4.2
|
41.0
|
1.0
|
|
HE2
|
F:LYS16
|
4.3
|
41.1
|
1.0
|
|
O3A
|
F:GTP201
|
4.3
|
32.3
|
1.0
|
|
CG
|
F:ASP57
|
4.3
|
40.0
|
1.0
|
|
HZ1
|
F:LYS16
|
4.4
|
41.1
|
1.0
|
|
HA
|
F:THR35
|
4.4
|
36.6
|
1.0
|
|
HZ2
|
F:LYS16
|
4.4
|
41.1
|
1.0
|
|
O1B
|
F:GTP201
|
4.4
|
32.9
|
1.0
|
|
O
|
F:ASP33
|
4.5
|
28.8
|
1.0
|
|
PA
|
F:GTP201
|
4.5
|
32.7
|
1.0
|
|
HA
|
F:PRO34
|
4.5
|
41.0
|
1.0
|
|
HG23
|
F:THR35
|
4.6
|
41.7
|
1.0
|
|
O1A
|
F:GTP201
|
4.6
|
32.2
|
1.0
|
|
O
|
F:THR58
|
4.6
|
42.4
|
1.0
|
|
O1G
|
F:GTP201
|
4.6
|
31.4
|
1.0
|
|
NZ
|
F:LYS16
|
4.7
|
34.2
|
1.0
|
|
HG22
|
F:THR35
|
4.7
|
41.7
|
1.0
|
|
HE1
|
F:TYR32
|
4.8
|
37.7
|
1.0
|
|
C
|
F:PRO34
|
4.8
|
32.8
|
1.0
|
|
CB
|
F:LYS16
|
4.8
|
33.1
|
1.0
|
|
C
|
F:LYS16
|
4.8
|
36.3
|
1.0
|
|
HOG3
|
F:GTP201
|
5.0
|
42.0
|
1.0
|
|
CE
|
F:LYS16
|
5.0
|
34.2
|
1.0
|
|
Reference:
A.K.Bera,
K.D.Westover.
Structural Basis of Impaired Hydrolysis in Kras Mutant To Be Published.
Page generated: Tue Oct 1 11:55:30 2024
|
