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Magnesium in PDB 6msa: Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A InhibitorsEnzymatic activity of Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors
All present enzymatic activity of Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors, PDB code: 6msa
was solved by
C.G.Jakob,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6msa:
The structure of Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors
(pdb code 6msa). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors, PDB code: 6msa: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6msaGo back to Magnesium Binding Sites List in 6msa
Magnesium binding site 1 out
of 2 in the Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6msaGo back to Magnesium Binding Sites List in 6msa
Magnesium binding site 2 out
of 2 in the Novel, Potent, Selective and Brain Penetrant Phosphodiesterase 10A Inhibitors
Mono view Stereo pair view
Reference:
H.Geneste,
K.Drescher,
C.Jakob,
L.Laplanche,
M.Ochse,
M.Torrent.
Novel, Potent, Selective, and Brain Penetrant Phosphodiesterase 10A Inhibitors. Bioorg. Med. Chem. Lett. V. 29 406 2019.
Page generated: Mon Dec 14 23:38:20 2020
ISSN: ESSN 1464-3405 PubMed: 30587449 DOI: 10.1016/J.BMCL.2018.12.029 |
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