Magnesium in PDB 6msm: Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)

All present enzymatic activity of Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr):
3.6.3.49;

The binding sites of Magnesium atom in the Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) (pdb code 6msm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr), PDB code: 6msm:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1501 b:0.3 occ:1.00 OG1 A:THR465 2.1 0.0 1.0 O2B A:ATP1503 2.1 0.7 1.0 O3G A:ATP1503 2.5 0.9 1.0 OE1 A:GLN493 2.5 0.9 1.0 OD1 A:ASP572 3.4 0.5 1.0 PB A:ATP1503 3.4 0.6 1.0 CB A:THR465 3.4 0.4 1.0 CD A:GLN493 3.4 0.4 1.0 PG A:ATP1503 3.7 0.4 1.0 N A:THR465 3.8 0.5 1.0 O3B A:ATP1503 3.8 0.3 1.0 NE2 A:GLN493 4.0 0.5 1.0 CA A:THR465 4.1 0.9 1.0 OD2 A:ASP572 4.1 0.8 1.0 O1B A:ATP1503 4.1 0.8 1.0 CG A:ASP572 4.1 0.7 1.0 O1G A:ATP1503 4.2 0.4 1.0 NZ A:LYS464 4.2 0.2 1.0 CG2 A:THR465 4.4 0.8 1.0 O2A A:ATP1503 4.6 0.3 1.0 CG A:GLN493 4.6 0.8 1.0 O3A A:ATP1503 4.6 0.5 1.0 CB A:LYS464 4.6 0.7 1.0 C A:LYS464 4.7 0.4 1.0 CB A:GLN493 4.8 0.2 1.0 O2G A:ATP1503 4.9 0.1 1.0 O1A A:ATP1503 4.9 0.4 1.0 PA A:ATP1503 4.9 0.4 1.0

Magnesium binding site 2 out of 2 in the Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Phosphorylated, Atp-Bound Human Cystic Fibrosis Transmembrane Conductance Regulator (Cftr) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1502 b:0.7 occ:1.00 O2B A:ATP1504 2.0 0.1 1.0 O3G A:ATP1504 2.2 0.1 1.0 OG A:SER1251 2.4 0.5 1.0 OE1 A:GLN1291 2.7 1.0 1.0 PB A:ATP1504 2.8 0.8 1.0 O1B A:ATP1504 3.1 0.8 1.0 PG A:ATP1504 3.3 0.9 1.0 O3B A:ATP1504 3.4 0.8 1.0 CD A:GLN1291 3.4 0.4 1.0 NE2 A:GLN1291 3.5 0.3 1.0 CB A:SER1251 3.6 0.1 1.0 OD1 A:ASP1370 3.7 0.8 1.0 N A:SER1251 3.8 0.0 1.0 O1G A:ATP1504 3.8 1.0 1.0 CA A:SER1251 4.2 0.2 1.0 O3A A:ATP1504 4.2 0.4 1.0 NZ A:LYS1250 4.4 0.1 1.0 CB A:LYS1250 4.4 0.1 1.0 OD2 A:ASP1370 4.4 0.6 1.0 CG A:ASP1370 4.5 0.2 1.0 O2G A:ATP1504 4.6 0.9 1.0 CE A:LYS1250 4.6 0.2 1.0 O1A A:ATP1504 4.6 0.5 1.0 C A:LYS1250 4.7 0.3 1.0 SG A:CYS1400 4.8 0.4 1.0 CG A:GLN1291 4.8 0.1 1.0 PA A:ATP1504 4.8 0.7 1.0 O2A A:ATP1504 4.9 0.8 1.0 CA A:LYS1250 5.0 0.8 1.0

Z.Zhang, F.Liu, J.Chen. Molecular Structure of the Atp-Bound, Phosphorylated Human Cftr. Proc. Natl. Acad. Sci. V. 115 12757 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30459277
DOI: 10.1073/PNAS.1815287115