Magnesium in PDB 6nce: Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence

The structure of Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence, PDB code: 6nce was solved by J.M.Rogers, S.M.Jarrett, T.C.Seegar, C.T.Waters, A.N.Hallworth, S.C.Blacklow, M.L.Bulyk, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.57 / 2.60
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	94.940, 102.080, 34.450, 90.00, 102.65, 90.00
R / Rfree (%)	23.5 / 27.1

The binding sites of Magnesium atom in the Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence (pdb code 6nce). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence, PDB code: 6nce:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:77.0 occ:1.00 O A:PHE172 2.0 0.1 1.0 O A:ASN169 2.7 87.2 1.0 O A:LEU166 3.0 0.8 1.0 C A:PHE172 3.1 99.5 1.0 O A:SER167 3.7 0.7 1.0 C A:ASN169 3.8 93.3 1.0 N A:PHE172 3.9 0.3 1.0 CA A:PHE172 3.9 0.5 1.0 C A:SER167 4.0 0.3 1.0 CB A:PHE172 4.1 96.4 1.0 C A:LEU166 4.1 0.8 1.0 N A:LYS173 4.2 0.8 1.0 N A:ASN169 4.3 87.5 1.0 CZ3 A:TRP189 4.3 99.3 1.0 CA A:LYS173 4.5 0.9 1.0 CA A:SER167 4.5 0.7 1.0 N A:LYS170 4.6 0.7 1.0 CA A:LYS170 4.6 0.2 1.0 C A:LYS170 4.6 95.7 1.0 CA A:ASN169 4.6 85.2 1.0 N A:LEU168 4.7 0.2 1.0 CD A:LYS173 4.7 95.5 1.0 N A:SER167 4.7 96.5 1.0 C A:LEU168 4.7 0.7 1.0 O A:LYS170 4.9 97.1 1.0 N A:CYS171 4.9 0.3 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Human FOXN3 Dna Binding Domain in Complex with A Forkhead Dna Sequence within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg101 b:0.8 occ:1.00 O D:HOH203 2.0 0.8 1.0 O D:HOH204 2.1 0.8 1.0 O2 D:DT13 3.7 0.1 1.0 O4' D:DA14 4.0 0.1 1.0 O4' C:DG7 4.3 0.7 1.0 C4' D:DA14 4.3 1.0 1.0 C4' C:DG7 4.4 99.9 1.0 C5' D:DA14 4.4 0.6 1.0 C5' C:DG7 4.4 0.2 1.0 C2 D:DT13 4.8 0.9 1.0 N3 C:DA6 4.8 0.9 1.0 C1' D:DT13 4.9 0.5 1.0

J.M.Rogers, C.T.Waters, T.C.M.Seegar, S.M.Jarrett, A.N.Hallworth, S.C.Blacklow, M.L.Bulyk. Bispecific Forkhead Transcription Factor FOXN3 Recognizes Two Distinct Motifs with Different Dna Shapes. Mol. Cell V. 74 245 2019.
ISSN: ISSN 1097-4164
PubMed: 30826165
DOI: 10.1016/J.MOLCEL.2019.01.019