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Magnesium in PDB 6p1v: Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming DcmpnppEnzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp
All present enzymatic activity of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp:
2.7.7.7; Protein crystallography data
The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp, PDB code: 6p1v
was solved by
A.M.Kaminski,
L.C.Pedersen,
K.Bebenek,
K.K.Chiruvella,
D.A.Ramsden,
T.A.Kunkel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 6p1v:
The structure of Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp
(pdb code 6p1v). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp, PDB code: 6p1v: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6p1vGo back to Magnesium Binding Sites List in 6p1v
Magnesium binding site 1 out
of 2 in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6p1vGo back to Magnesium Binding Sites List in 6p1v
Magnesium binding site 2 out
of 2 in the Pre-Catalytic Ternary Complex of Human Dna Polymerase Mu with 1-Nt Gapped Substrate Containing Undamaged Template Dg and Bound Incoming Dcmpnpp
Mono view Stereo pair view
Reference:
A.M.Kaminski,
K.K.Chiruvella,
D.A.Ramsden,
T.A.Kunkel,
K.Bebenek,
L.C.Pedersen.
Unexpected Behavior of Dna Polymerase Mu Opposite Template 8-Oxo-7,8-Dihydro-2'-Guanosine. Nucleic Acids Res. V. 47 9410 2019.
Page generated: Mon Dec 14 23:45:44 2020
ISSN: ESSN 1362-4962 PubMed: 31435651 DOI: 10.1093/NAR/GKZ680 |
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