|
Magnesium in PDB 6p8e: Crystal Structure of CDK4 in Complex with CYCLIND1 and P27Enzymatic activity of Crystal Structure of CDK4 in Complex with CYCLIND1 and P27
All present enzymatic activity of Crystal Structure of CDK4 in Complex with CYCLIND1 and P27:
2.7.11.22; Protein crystallography data
The structure of Crystal Structure of CDK4 in Complex with CYCLIND1 and P27, PDB code: 6p8e
was solved by
K.Z.Guiley,
J.W.Stevenson,
K.Lou,
K.J.Barkovich,
K.Bunch,
S.M.Tripathi,
K.M.Shokat,
S.M.Rubin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of CDK4 in Complex with CYCLIND1 and P27
(pdb code 6p8e). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of CDK4 in Complex with CYCLIND1 and P27, PDB code: 6p8e: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 6p8eGo back to Magnesium Binding Sites List in 6p8e
Magnesium binding site 1 out
of 2 in the Crystal Structure of CDK4 in Complex with CYCLIND1 and P27
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 6p8eGo back to Magnesium Binding Sites List in 6p8e
Magnesium binding site 2 out
of 2 in the Crystal Structure of CDK4 in Complex with CYCLIND1 and P27
Mono view Stereo pair view
Reference:
K.Z.Guiley,
J.W.Stevenson,
K.Lou,
K.J.Barkovich,
V.Kumarasamy,
T.U.Wijeratne,
K.L.Bunch,
S.Tripathi,
E.S.Knudsen,
A.K.Witkiewicz,
K.M.Shokat,
S.M.Rubin.
P27 Allosterically Activates Cyclin-Dependent Kinase 4 and Antagonizes Palbociclib Inhibition. Science V. 366 2019.
Page generated: Mon Dec 14 23:46:49 2020
ISSN: ESSN 1095-9203 PubMed: 31831640 DOI: 10.1126/SCIENCE.AAW2106 |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |