Magnesium in PDB 6qdb: Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081

Enzymatic activity of Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081

All present enzymatic activity of Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081:
2.3.1.97;

Protein crystallography data

The structure of Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081, PDB code: 6qdb was solved by J.A.Brannigan, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	39.92 / 1.40
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	47.860, 90.870, 53.200, 90.00, 111.92, 90.00
*R / R_free (%)*	15.6 / 18.4

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081 (pdb code 6qdb). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081, PDB code: 6qdb:

Magnesium binding site 1 out of 1 in 6qdb

Go back to

Magnesium Binding Sites List in 6qdb

Magnesium binding site 1 out of 1 in the Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Leishmania Major N-Myristoyltransferase in Complex with Thienopyrimidine Inhibitor Imp-0000081 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mg1004 b:18.1 occ:1.00	O	A:LEU175	2.7	12.8	1.0
	O1A	A:MYA1001	2.8	10.2	1.0
	N	A:LYS178	2.9	13.7	1.0
	N	A:LEU180	3.1	10.1	1.0
	O5A	A:MYA1001	3.1	10.4	1.0
	N	A:ARG179	3.3	11.8	1.0
	N	A:GLU177	3.5	11.9	1.0
	CB	A:LEU180	3.5	11.8	1.0
	CA	A:LYS178	3.5	14.1	1.0
	C	A:LYS178	3.5	12.9	1.0
	CB	A:LYS178	3.7	15.1	1.0
	P1A	A:MYA1001	3.7	10.2	1.0
	O2A	A:MYA1001	3.7	11.8	1.0
	C	A:ARG176	3.8	13.1	1.0
	CA	A:LEU180	3.8	11.1	1.0
	C	A:LEU175	3.9	11.8	1.0
	C	A:GLU177	3.9	15.1	1.0
	CA	A:ARG176	4.1	12.1	1.0
	CG1	A:VAL171	4.1	9.8	1.0
	C	A:ARG179	4.1	12.0	1.0
	CA	A:GLU177	4.1	14.2	1.0
	CA	A:ARG179	4.2	12.7	1.0
	P2A	A:MYA1001	4.2	10.1	1.0
	N	A:ALA181	4.3	9.5	1.0
	O3A	A:MYA1001	4.3	10.5	1.0
	O	A:LYS178	4.3	14.2	1.0
	N	A:ARG176	4.4	11.6	1.0
	CG	A:LYS178	4.6	19.3	1.0
	C	A:LEU180	4.6	10.2	1.0
	O	A:ARG176	4.6	14.7	1.0
	O6A	A:MYA1001	4.7	10.1	1.0
	CG2	A:VAL171	4.8	9.1	1.0
	CG	A:LEU180	4.8	13.2	1.0
	CB	A:VAL171	4.9	8.0	1.0

Reference:

J.A.Brannigan, J.A.Brannigan. N/A N/A.

Page generated: Tue Oct 1 15:27:14 2024

Last articles

W in 8QLN
W in 8RJA
V in 8WTN
Te in 8QLN
Re in 9GHX
Rb in 8Z5C
Ni in 9C0T
Ni in 9C0S
Ni in 9GP1
Ni in 9FYO

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy